ZNF417 and STX11

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZNF417	STX11
Description		zinc finger protein 417	syntaxin 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Golgi Apparatus Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane SNARE Complex Presynaptic Membrane Presynaptic Active Zone Membrane
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated	Intracellular Protein Transport Exocytosis Vesicle Fusion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Membrane Fusion
Pathways		Generic Transcription Pathway
Drugs
Diseases			Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
GWAS		Depression in smokers ( 30219690)	Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		68 interacting genes: ADAMTSL4 BEGAIN BEND5 CARD9 CCDC136 CCDC57 CCDC85B CCNDBP1 CEP44 CEP70 CEP72 CSRNP1 EFS FHL2 FHL3 FSD2 GOLGA2 HMBOX1 IKZF1 KLC3 KRT15 KRT38 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 KRTAP5-9 KXD1 LURAP1 LZTS2 MDFI MEOX2 MID2 MTUS2 NDEL1 NINL NOTCH2NLA PHC2 PLSCR1 PNMA2 PRPF31 REL RPGRIP1 RUNDC3A SPRY2 SSX2IP STX11 TCF4 TFIP11 TMCC2 TNS2 TRAF1 TRIM27 TRIM36 TRIM37 TRIM41 TRIM54 TSGA10 ZBTB1 ZBTB10 ZBTB43 ZBTB8A ZNF587	64 interacting genes: APP AXIN1 BLOC1S6 BYSL C1orf109 CARD9 CCBE1 CCDC184 CCDC33 CCNK CDCA7L CRYBA4 CTBP2 CWF19L2 EIF1AD FAM110A FAM161A FAM74A4 FAM90A1 FARS2 GOLGA8EP GOLGA8F HAUS1 HGS IKBKG IKZF3 KAT5 KCTD9 KDM1A KLC3 KXD1 LENG1 LONRF1 MBIP MEOX2 MFAP1 MID2 NDC80 NTAQ1 PPP1R18 PRKAB2 PRPF31 PSMA3 PSMC3 RNF6 RUNX1T1 SH2D4A SLC38A2 SMARCE1 SNAP23 SNAP25 SNX3 SUV39H1 TAF6L TBK1 TCF4 TLE5 TNFRSF21 USHBP1 VAMP2 VPS52 ZCCHC10 ZNF417 ZNF587
Entrez ID		147687	8676
HPRD ID		18341	09231
Ensembl ID		ENSG00000173480	ENSG00000135604
Uniprot IDs		M0R230 Q8TAU3	O75558
PDB IDs
Enriched GO Terms of Interacting Partners?
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