TYSND1 and TH

Number of citations of the paper that reports this interaction (PubMedID 22002062)
16

Data Source:
BioGRID (enzymatic study)

		TYSND1	TH
Description		trypsin domain containing 1	tyrosine hydroxylase
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Matrix Cytosol Membrane	Cell Nucleus Cytoplasm Mitochondrion Smooth Endoplasmic Reticulum Cytosol Synaptic Vesicle Cytoplasmic Side Of Plasma Membrane Axon Dendrite Cytoplasmic Vesicle Melanosome Membrane Neuron Projection Terminal Bouton Perikaryon
	Molecular Function	Protease Binding Serine-type Endopeptidase Activity	Tyrosine 3-monooxygenase Activity Protein Binding Ferrous Iron Binding Ferric Iron Binding Amino Acid Binding Oxygen Binding Enzyme Binding Protein Domain Specific Binding Tetrahydrobiopterin Binding Dopamine Binding
	Biological Process	Proteolysis Protein Targeting To Peroxisome Protein Processing Regulation Of Fatty Acid Beta-oxidation	Response To Hypoxia Synaptic Transmission, Dopaminergic Response To Amphetamine Heart Morphogenesis Dopamine Biosynthetic Process From Tyrosine Fatty Acid Metabolic Process Sphingolipid Metabolic Process Heart Development Visual Perception Sensory Perception Of Sound Learning Memory Mating Behavior Locomotory Behavior Regulation Of Heart Contraction Response To Water Deprivation Response To Light Stimulus Response To Herbicide Response To Salt Stress Anatomical Structure Morphogenesis Animal Organ Morphogenesis Response To Zinc Ion Multicellular Organism Aging Response To Activity Aminergic Neurotransmitter Loading Into Synaptic Vesicle Glycoside Metabolic Process Phthalate Metabolic Process Cerebral Cortex Development Response To Nutrient Levels Response To Estradiol Response To Lipopolysaccharide Isoquinoline Alkaloid Metabolic Process Social Behavior Response To Isolation Stress Response To Immobilization Stress Neurotransmitter Biosynthetic Process Terpene Metabolic Process Dopamine Biosynthetic Process Epinephrine Biosynthetic Process Norepinephrine Biosynthetic Process Catecholamine Biosynthetic Process Eye Photoreceptor Cell Development Circadian Sleep/wake Cycle Eating Behavior Response To Peptide Hormone Pigmentation Response To Ethanol Response To Ether Response To Pyrethroid Embryonic Camera-type Eye Morphogenesis Response To Corticosterone Response To Electrical Stimulus Phytoalexin Metabolic Process Oxidation-reduction Process Cellular Response To Manganese Ion Cellular Response To Alkaloid Cellular Response To Nicotine Cellular Response To Glucose Stimulus Cellular Response To Growth Factor Stimulus
Pathways		Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins TYSND1 cleaves peroxisomal proteins	Catecholamine biosynthesis
Drugs			L-Phenylalanine L-Tyrosine Sapropterin Metyrosine 3-Tyrosine
Diseases			Primary torsion dystonia (PTD)
GWAS			Celiac disease ( 23936387) Height ( 31562340) Prostate cancer ( 19767753) Prostate cancer (early onset) ( 24740154) Prostate cancer (SNP x SNP interaction) ( 22219177) Type 1 diabetes autoantibodies in high risk HLA genotype individuals (time to event) ( 29310926) Type 1 diabetes in high risk HLA genotype individuals (time to event) ( 29310926) Type 2 diabetes ( 31324766 25102180)
Interacting Genes		3 interacting genes: ACOX1 OIT3 TH	12 interacting genes: CAMK2G CDK11B CSNK2A1 MAPK1 MAPK3 MAPKAPK2 PRKACA RPS6KA5 SNCA TYSND1 YWHAB YWHAZ
Entrez ID		219743	7054
HPRD ID		15593	01865
Ensembl ID		ENSG00000156521	ENSG00000180176
Uniprot IDs		Q2T9J0	P07101 P78428
PDB IDs			2XSN 4J6S
Enriched GO Terms of Interacting Partners?
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