STOM and MT2A

		STOM	MT2A
Description		stomatin	metallothionein 2A
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Endoplasmic Reticulum Cytoskeleton Plasma Membrane Integral Component Of Plasma Membrane Membrane Vesicle Azurophil Granule Membrane Specific Granule Membrane Melanosome Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Tertiary Granule Membrane Blood Microparticle	Cell Nucleus Cytoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity RNA Polymerase Binding	Protein Binding Drug Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Neutrophil Degranulation Positive Regulation By Host Of Viral Genome Replication Positive Regulation Of Protein Targeting To Membrane Regulation Of Acid-sensing Ion Channel Activity	Cellular Copper Ion Homeostasis Cellular Zinc Ion Homeostasis Response To Metal Ion Detoxification Of Copper Ion Cellular Response To Drug Cellular Response To Interleukin-3 Cellular Response To Erythropoietin Negative Regulation Of Growth Interferon-gamma-mediated Signaling Pathway Cellular Response To Cadmium Ion Cellular Response To Copper Ion Cellular Response To Zinc Ion
Pathways		Stimuli-sensing channels Neutrophil degranulation	Metallothioneins bind metals Metallothioneins bind metals Interferon gamma signaling
Drugs			Zinc
Diseases		Hereditary stomatocytosis (HSt); Dehydrated hereditary stomatocytosis (DHS); Overhydrated hereditary stomatocytosis (OHS); Familial pseudohyperkalemia (FP)
GWAS
Interacting Genes		17 interacting genes: ASIC1 ASIC2 ASIC3 ASS1 CRAT DVL3 FPGS LANCL1 MT2A NUP214 PSMB7 RPL13A RUVBL1 RUVBL2 SLC2A1 STXBP1 VAV2	20 interacting genes: ADAMTS4 ARF6 ASS1 BARD1 DHODH ECT2 EOLA1 HMGB1 JMJD1C LAMTOR5 MCPH1 PAXIP1 PRKD1 RCHY1 RIN3 SHBG SPINK7 STOM TNS2 USP25
Entrez ID		2040	4502
HPRD ID		00585	08863
Ensembl ID		ENSG00000148175	ENSG00000125148
Uniprot IDs		A0A024R882 F8VSL7 P27105	P02795
PDB IDs			1MHU 2MHU
Enriched GO Terms of Interacting Partners?
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