STOM and ASIC1

Number of citations of the paper that reports this interaction (PubMedID 15471860)
39

Data Source:
HPRD (in vivo)

		STOM	ASIC1
Description		stomatin	acid sensing ion channel subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Endoplasmic Reticulum Cytoskeleton Plasma Membrane Integral Component Of Plasma Membrane Membrane Vesicle Azurophil Granule Membrane Specific Granule Membrane Melanosome Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Tertiary Granule Membrane Blood Microparticle	Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Synapse
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity RNA Polymerase Binding	Protein Binding Ligand-gated Sodium Channel Activity Ion Gated Channel Activity Acid-sensing Ion Channel Activity
	Biological Process	Neutrophil Degranulation Positive Regulation By Host Of Viral Genome Replication Positive Regulation Of Protein Targeting To Membrane Regulation Of Acid-sensing Ion Channel Activity	Behavioral Fear Response Response To Amphetamine Sodium Ion Transport Signal Transduction Memory Associative Learning Response To PH Response To Acidic PH Ion Transmembrane Transport Sodium Ion Transmembrane Transport Regulation Of Membrane Potential Negative Regulation Of Neurotransmitter Secretion Sensory Perception Of Sour Taste Protein Homotrimerization Calcium Ion Transmembrane Transport Cellular Response To PH
Pathways		Stimuli-sensing channels Neutrophil degranulation	Stimuli-sensing channels
Drugs			Diclofenac Amiloride
Diseases		Hereditary stomatocytosis (HSt); Dehydrated hereditary stomatocytosis (DHS); Overhydrated hereditary stomatocytosis (OHS); Familial pseudohyperkalemia (FP)
GWAS
Interacting Genes		17 interacting genes: ASIC1 ASIC2 ASIC3 ASS1 CRAT DVL3 FPGS LANCL1 MT2A NUP214 PSMB7 RPL13A RUVBL1 RUVBL2 SLC2A1 STXBP1 VAV2	5 interacting genes: ASIC2 ATXN3 PICK1 PRKACA STOM
Entrez ID		2040	41
HPRD ID		00585	04182
Ensembl ID		ENSG00000148175	ENSG00000110881
Uniprot IDs		A0A024R882 F8VSL7 P27105	A8K1U5 P78348
PDB IDs
Enriched GO Terms of Interacting Partners?
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