CRTC2 and SIK3

Number of citations of the paper that reports this interaction (PubMedID 16306228)
45

Data Source:
HPRD (in vivo, in vitro)

		CRTC2	SIK3
Description		CREB regulated transcription coactivator 2	SIK family kinase 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Extracellular Exosome	Cytoplasm
	Molecular Function	Chromatin Binding Protein Binding CAMP Response Element Binding Protein Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Tau-protein Kinase Activity
	Biological Process	Gluconeogenesis Viral Process Positive Regulation Of CREB Transcription Factor Activity Glucose Homeostasis Histone H3-K9 Acetylation Positive Regulation Of Transcription By RNA Polymerase II Protein Homotetramerization Toxin Transport	Microtubule Cytoskeleton Organization Protein Phosphorylation Intracellular Signal Transduction Positive Regulation Of TORC1 Signaling Positive Regulation Of TORC2 Signaling
Pathways		Transcriptional activation of mitochondrial biogenesis Circadian Clock
Drugs
Diseases
GWAS		Age at first birth ( 27798627) Empathy quotient ( 29527006)	Allergic rhinitis ( 30013184) Blood protein levels ( 28240269) Delirium ( 29631748) Eosinophil counts ( 27863252) Eosinophil percentage of white cells ( 27863252) HDL cholesterol ( 31170924 24886709) Hearing function ( 25060954) Medication use (thyroid preparations) ( 31015401) Metabolic syndrome ( 30382898) Non-accommodative esotropia ( 30098192) Response to Vitamin E supplementation ( 22437554) Sum eosinophil basophil counts ( 27863252) Triglyceride levels ( 29615537) Triglycerides ( 24886709)
Interacting Genes		9 interacting genes: MFHAS1 PPP3CA PRKAA1 SIK1 SIK2 SIK3 YWHAB YWHAG YWHAZ	7 interacting genes: ATP5MG CRTC2 HDAC5 PRKACA TRAF1 TRIP6 YWHAZ
Entrez ID		200186	23387
HPRD ID		12347	11121
Ensembl ID		ENSG00000160741	ENSG00000160584
Uniprot IDs		Q53ET0	A1A5A9 Q9Y2K2
PDB IDs		4HTM
Enriched GO Terms of Interacting Partners?
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