ELF4 and FBXO4

Number of citations of the paper that reports this interaction (PubMedID 16581786)
16

Data Source:
HPRD (in vivo)

		ELF4	FBXO4
Description		E74 like ETS transcription factor 4	F-box protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Nuclear Body PML Body	Ubiquitin Ligase Complex Cell Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process	Natural Killer Cell Proliferation NK T Cell Proliferation Regulation Of Transcription By RNA Polymerase II Cell Differentiation Innate Immune Response Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Protein Polyubiquitination Aging Posttranscriptional Regulation Of Gene Expression Protein Ubiquitination Cellular Homeostasis SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Ubiquitination Regulation Of Protein Stability Protein Destabilization Positive Regulation Of Telomere Maintenance Via Telomerase Common Myeloid Progenitor Cell Proliferation Post-translational Protein Modification Negative Regulation Of Fibroblast Proliferation Cellular Response To Ionizing Radiation Negative Regulation Of Protein Localization To Nucleus Positive Regulation Of Protein Polyubiquitination Regulation Of DNA Damage Checkpoint
Pathways			Association of TriC/CCT with target proteins during biosynthesis Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)
Interacting Genes		10 interacting genes: CASP4 FBXO4 FBXO7 NPM1 PML PSMD8 RUNX1 SET SKP2 UBB	7 interacting genes: CCND1 CDC34 ELF4 FXR1 SKP1 TERF1 UBE2D2
Entrez ID		2000	26272
HPRD ID		06499	09949
Ensembl ID		ENSG00000102034	ENSG00000151876
Uniprot IDs		Q99607	B3KNA0 D6RAJ6 Q9UKT5
PDB IDs			3L2O 3L82
Enriched GO Terms of Interacting Partners?
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