EIF5A and DHPS

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)
HPRD (in vivo, in vitro)

		EIF5A	DHPS
Description		eukaryotic translation initiation factor 5A	deoxyhypusine synthase
Image
GO Annotations	Cellular Component	Nucleus Annulate Lamellae Nuclear Pore Cytoplasm Endoplasmic Reticulum Membrane Cytosol Membrane	Cytoplasm Cytosol
	Molecular Function	RNA Binding Translation Elongation Factor Activity Protein Binding U6 SnRNA Binding Ribosome Binding Protein N-terminus Binding	Protein Binding Deoxyhypusine Synthase Activity Identical Protein Binding
	Biological Process	MRNA Export From Nucleus Translational Frameshifting Protein Export From Nucleus Nucleocytoplasmic Transport Apoptotic Process Positive Regulation Of Cell Proliferation Positive Regulation Of Translational Elongation Positive Regulation Of Translational Termination	Translation Spermidine Metabolic Process Positive Regulation Of Cell Proliferation Peptidyl-lysine Modification To Peptidyl-hypusine
Pathways		Hypusine synthesis from eIF5A-lysine	Hypusine synthesis from eIF5A-lysine
Drugs			1-Guanidinium-7-Aminoheptane
Diseases
GWAS		Venous thromboembolism ( 31420334)
Interacting Genes		12 interacting genes: CRX DHPS DOHH ESR1 MEOX2 REL RPL5 STUB1 TGM2 XPO1 XPO4 XRN2	13 interacting genes: BRCA1 EIF5A EIF5A2 NIF3L1 NTAQ1 NUDT18 PTPRH RAB27B REL RPL9 UPF1 VASH1 ZNF138
Entrez ID		1984	1725
HPRD ID		02555	02969
Ensembl ID		ENSG00000132507	ENSG00000095059
Uniprot IDs		P63241	A0A024R7D0 A0A024R7E9 P49366
PDB IDs		1FH4 3CPF 5DLQ	1DHS 1RLZ 1ROZ 1RQD
Enriched GO Terms of Interacting Partners?
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