E2F2 and CDK3

Number of citations of the paper that reports this interaction (PubMedID 8846921)
28

Data Source:
HPRD (in vivo)

		E2F2	CDK3
Description		E2F transcription factor 2	cyclin dependent kinase 3
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm RNA Polymerase II Transcription Factor Complex	Nucleus
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific DNA Binding Protein Dimerization Activity	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Sprouting Angiogenesis Lens Fiber Cell Apoptotic Process	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Proliferation G0 To G1 Transition Cell Division Regulation Of Cell Cycle
Pathways		Oxidative Stress Induced Senescence Oncogene Induced Senescence CDC6 association with the ORC:origin complex Cyclin D associated events in G1
Drugs
Diseases
GWAS		Eosinophil counts ( 27863252) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red cell distribution width ( 27863252 28957414) Sum eosinophil basophil counts ( 27863252) White blood cell count ( 27863252)
Interacting Genes		19 interacting genes: ARID3A ATAD2 BCAR1 BRD2 CDK3 FHL2 GIT2 GNB5 GRB2 KMT5A RB1 RNF144A RYBP SP1 SPIB TFDP1 TFDP2 UCHL5 YY1	18 interacting genes: APP CABLES1 CABLES2 CCNA2 CCNC CCNE1 CCNE2 CDC37 CDKN1A CDKN1B CDKN3 E2F1 E2F2 E2F3 KIR3DL1 NEDD4L PPARA RB1
Entrez ID		1870	1018
HPRD ID		02692	00446
Ensembl ID		ENSG00000007968	ENSG00000250506
Uniprot IDs		Q14209	Q00526
PDB IDs		1N4M	1LFN
Enriched GO Terms of Interacting Partners?
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