CDK3 and E2F2

Number of citations of the paper that reports this interaction (PubMedID 8846921)
28

Data Source:
HPRD (in vivo)

		CDK3	E2F2
Description		cyclin dependent kinase 3	E2F transcription factor 2
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GO Annotations	Cellular Component	Nucleus	Nuclear Chromatin Nucleus Nucleoplasm RNA Polymerase II Transcription Factor Complex
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific DNA Binding Protein Dimerization Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Proliferation G0 To G1 Transition Cell Division Regulation Of Cell Cycle	Negative Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Sprouting Angiogenesis Lens Fiber Cell Apoptotic Process
Pathways			Oxidative Stress Induced Senescence Oncogene Induced Senescence CDC6 association with the ORC:origin complex Cyclin D associated events in G1
Drugs
Diseases
GWAS			Eosinophil counts ( 27863252) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red cell distribution width ( 27863252 28957414) Sum eosinophil basophil counts ( 27863252) White blood cell count ( 27863252)
Interacting Genes		18 interacting genes: APP CABLES1 CABLES2 CCNA2 CCNC CCNE1 CCNE2 CDC37 CDKN1A CDKN1B CDKN3 E2F1 E2F2 E2F3 KIR3DL1 NEDD4L PPARA RB1	19 interacting genes: ARID3A ATAD2 BCAR1 BRD2 CDK3 FHL2 GIT2 GNB5 GRB2 KMT5A RB1 RNF144A RYBP SP1 SPIB TFDP1 TFDP2 UCHL5 YY1
Entrez ID		1018	1870
HPRD ID		00446	02692
Ensembl ID		ENSG00000250506	ENSG00000007968
Uniprot IDs		Q00526	Q14209
PDB IDs		1LFN	1N4M
Enriched GO Terms of Interacting Partners?
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