ARID3A and E2F2

Number of citations of the paper that reports this interaction (PubMedID 15017387)
9

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		ARID3A	E2F2
Description		AT-rich interaction domain 3A	E2F transcription factor 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Membrane Raft	Nuclear Chromatin Nucleus Nucleoplasm RNA Polymerase II Transcription Factor Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Identical Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific DNA Binding Protein Dimerization Activity
	Biological Process	DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Sprouting Angiogenesis Lens Fiber Cell Apoptotic Process
Pathways		TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	Oxidative Stress Induced Senescence Oncogene Induced Senescence CDC6 association with the ORC:origin complex Cyclin D associated events in G1
Drugs
Diseases
GWAS		Immature fraction of reticulocytes ( 27863252) Primary biliary cholangitis ( 28425483) Systemic lupus erythematosus ( 28714469) Vertical cup-disc ratio ( 20548946)	Eosinophil counts ( 27863252) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red cell distribution width ( 27863252 28957414) Sum eosinophil basophil counts ( 27863252) White blood cell count ( 27863252)
Interacting Genes		12 interacting genes: APP BTK DSP E2F1 E2F2 E2F4 NOTCH2NLA PML SP100 TP53 TTC32 UBE2E3	19 interacting genes: ARID3A ATAD2 BCAR1 BRD2 CDK3 FHL2 GIT2 GNB5 GRB2 KMT5A RB1 RNF144A RYBP SP1 SPIB TFDP1 TFDP2 UCHL5 YY1
Entrez ID		1820	1870
HPRD ID		10343	02692
Ensembl ID		ENSG00000116017	ENSG00000007968
Uniprot IDs		Q99856	Q14209
PDB IDs		2KK0 4LJX	1N4M
Enriched GO Terms of Interacting Partners?
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