TCEANC and VAC14

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TCEANC	VAC14
Description		transcription elongation factor A N-terminal and central domain containing	VAC14 component of PIKFYVE complex
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Golgi Membrane Extrinsic Component Of Vacuolar Membrane Vacuolar Membrane Endoplasmic Reticulum Cytosol Endosome Membrane Early Endosome Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle PAS Complex
	Molecular Function	Protein Binding	Protein Binding Signaling Receptor Activity
	Biological Process	Transcription, DNA-templated	Phosphatidylinositol Biosynthetic Process Signal Transduction Viral Process Positive Regulation Of Kinase Activity
Pathways			Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the late endosome membrane
Drugs
Diseases
GWAS			Diffuse cutaneous systemic sclerosis ( 29293537) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) High density lipoprotein cholesterol levels ( 28548082) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Pulse pressure ( 28135244)
Interacting Genes		38 interacting genes: APP ATXN1 BRCA1 CARD9 CBY2 CCDC85B CRACR2B CSRNP1 DAB1 FAM9B FBXO25 FSD2 GOLGA2 HMBOX1 IKBKG KIFC3 KRTAP10-7 KRTAP4-2 KRTAP5-9 LMNA LURAP1 MAGEA11 MEOX1 MID1 NAB2 NEDD4 NINL OBI1 PNMA1 RAD54B SSNA1 TARBP2 TRAF2 VAC14 VPS52 YWHAE ZBTB14 ZKSCAN7	53 interacting genes: ACSS1 APP ASB13 BCL2L1 BHLHE40 C11orf54 C4orf33 CASP1 CCDC103 CD209 CDRT4 CNTN2 COL8A1 CRK DDAH2 FNDC3B GALT GINS3 HNRNPLL JMJD7 KRTAP19-5 KRTAP19-7 KYAT1 LINC00518 LPAL2 MGAT5B MPPED2 MTMR9 MVP NGB NOS1 NTAQ1 PCMTD2 PDE4DIP PELI1 PHF1 PHYKPL PIKFYVE PPP2CA PRADC1 PRR13 PRR20A RBFOX2 RHOXF2 SIGLEC5 SMUG1 SNF8 SPRYD7 SRPK2 TCEANC TP53BP1 ZCWPW1 ZNF34
Entrez ID		170082	55697
HPRD ID		19501	07660
Ensembl ID		ENSG00000176896	ENSG00000103043
Uniprot IDs		A8K5F6 B4DG85 Q8N8B7	Q08AM6
PDB IDs
Enriched GO Terms of Interacting Partners?
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