SPPL2C and RETREG3

		SPPL2C	RETREG3
Description		signal peptide peptidase like 2C	reticulophagy regulator family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi-associated Vesicle Membrane Integral Component Of Cytoplasmic Side Of Endoplasmic Reticulum Membrane Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane	Integral Component Of Membrane Protein-containing Complex
	Molecular Function	Aspartic Endopeptidase Activity, Intramembrane Cleaving Protein Homodimerization Activity	Protein Binding
	Biological Process	Membrane Protein Ectodomain Proteolysis Membrane Protein Intracellular Domain Proteolysis Membrane Protein Proteolysis	Positive Regulation Of Neuron Projection Development
Pathways
Drugs
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Chronic obstructive pulmonary disease ( 30804561) Hand grip strength ( 29691431) Idiopathic pulmonary fibrosis ( 24429156) Male-pattern baldness ( 28196072) Neuroticism ( 29255261) Parkinson's disease ( 28892059) Red blood cell count ( 27863252)	Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		1 interacting genes: RETREG3	9 interacting genes: ABHD16A ARHGAP27 ARL6IP1 GABARAPL1 KANSL1 MAP1LC3A RUNDC1 SPPL2C STAP1
Entrez ID		162540	162427
HPRD ID		07085	14108
Ensembl ID		ENSG00000185294	ENSG00000141699
Uniprot IDs		Q8IUH8	K7EQI9 Q86VR2
PDB IDs
Enriched GO Terms of Interacting Partners?
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