ZFPM1 and CTBP2

Number of citations of the paper that reports this interaction (PubMedID 9724649)
117

Data Source:
HPRD (in vitro, two hybrid)

		ZFPM1	CTBP2
Description		zinc finger protein, FOG family member 1	C-terminal binding protein 2
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Transcriptional Repressor Complex	Nucleus Transcriptional Repressor Complex Cell Junction Photoreceptor Ribbon Synapse Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse GABA-ergic Synapse Presynaptic Cytosol
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Transcription Factor Binding Metal Ion Binding	Chromatin Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Protein Kinase Binding Retinoic Acid Receptor Binding Protein-containing Complex Binding NAD Binding Structural Constituent Of Presynaptic Active Zone
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II T-helper Cell Lineage Commitment Outflow Tract Morphogenesis Atrioventricular Valve Morphogenesis Mitral Valve Formation Tricuspid Valve Formation Heart Development Blood Coagulation Regulation Of Definitive Erythrocyte Differentiation Cell Differentiation Erythrocyte Differentiation Megakaryocyte Differentiation Platelet Formation Granulocyte Differentiation Negative Regulation Of Protein Binding Regulation Of Chemokine Production Embryonic Hemopoiesis Megakaryocyte Development Positive Regulation Of Interferon-gamma Biosynthetic Process Negative Regulation Of Interleukin-4 Biosynthetic Process Negative Regulation Of Fat Cell Differentiation Regulation Of Megakaryocyte Differentiation Cardiac Muscle Tissue Morphogenesis Definitive Erythrocyte Differentiation Primitive Erythrocyte Differentiation Negative Regulation Of Mast Cell Differentiation Ventricular Septum Morphogenesis Atrial Septum Morphogenesis Transcriptional Activation By Promoter-enhancer Looping	Negative Regulation Of Cell Proliferation Synaptic Vesicle Docking Viral Genome Replication Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Maintenance Of Presynaptic Active Zone Structure White Fat Cell Differentiation Oxidation-reduction Process Cellular Response To Leukemia Inhibitory Factor
Pathways		RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Factors involved in megakaryocyte development and platelet production	Repression of WNT target genes TCF7L2 mutants don't bind CTBP
Drugs
Diseases
GWAS		Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Bone mineral accretion in asthma (oral corticosteroid dose interaction) ( 26025128) Calcium levels ( 29403010) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Hair color ( 26926045) Hematocrit ( 27863252) LDL cholesterol ( 30275531) Low density lipoprotein cholesterol levels ( 29083408) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Platelet count ( 29403010 27863252) Plateletcrit ( 27863252) Red blood cell count ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Sum eosinophil basophil counts ( 27863252) Testicular germ cell tumor ( 28604728 28604732 26503584) Vascular endothelial growth factor levels ( 26910538) White blood cell count (basophil) ( 29403010 27863252)	Age-related cognitive decline (visuospatial skill) (slope of z-scores) ( 30954325) Body mass index ( 25673413 29273807) Chronotype ( 30696823) Diastolic blood pressure ( 30224653) Height ( 25429064) Infant, child and juvenile death in continuous marriage (proportion of children died <15 years) ( 30188897) Menarche (age at onset) ( 25231870) Prostate cancer ( 18264096) Vigorous physical activity ( 29899525)
Interacting Genes		6 interacting genes: CTBP2 GATA1 GATA2 GIPC1 GSK3B TOP3B	67 interacting genes: ACTG1 AKTIP APP ATE1 BAZ2B BCAS3 BCL3 C15orf39 CASP8AP2 CBX4 CCNH CCR5 CDKN2A CTBP1 CTPS2 DMRTB1 DVL2 EEF1D ELAC2 EP300 FHL3 FLI1 FOXP2 FUNDC1 H3-4 HIC1 HOXB5 IKZF2 KCNIP3 KLF3 KLF8 MDM2 MECOM NOL4 NOL4L NRIP1 PLCB1 PNN PPP1R15A PROX1 PSMF1 RAI2 RIMBP3 RPL17 RPL7A RPS28 RPS29 RPS4X RUNX1 SOX13 SOX6 STUB1 STX11 TEAD3 TGIF1 TSHZ3 UBC UBE2I XRCC6 ZBP1 ZBTB18 ZEB1 ZEB2 ZFPM1 ZFPM2 ZNF512B ZNF750
Entrez ID		161882	1488
HPRD ID		11800	04016
Ensembl ID		ENSG00000179588	ENSG00000175029
Uniprot IDs		Q8IX07	P56545
PDB IDs		2XU7	2OME 4LCJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?