RBMY1F and CBX2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RBMY1F	CBX2
Description		RNA binding motif protein Y-linked family 1 member F	chromobox 2
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus Nuclear Speck	Euchromatin Heterochromatin Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding	DNA Binding Chromatin Binding Protein Binding Methylated Histone Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Spermatogenesis MRNA Cis Splicing, Via Spliceosome	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Cell Differentiation Development Of Primary Sexual Characteristics
Pathways			Oxidative Stress Induced Senescence SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases			46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS
Interacting Genes		17 interacting genes: AEN APOBEC3C CBX2 CIRBP CLK3 DAAM2 HNRNPK PCDHB14 PRPF31 PRR3 RAMAC RASD1 RBM10 RBM3 RBMX YTHDC1 ZNF385C	15 interacting genes: DHX57 H3-4 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP2-4 KRTAP4-12 MDFI PCGF2 PHC2 RBMY1A1 RBMY1F RNF2 RYBP
Entrez ID		159163	84733
HPRD ID		15232	14397
Ensembl ID		ENSG00000169800	ENSG00000173894
Uniprot IDs		Q15415	Q14781
PDB IDs			2D9U 3H91 5EPK
Enriched GO Terms of Interacting Partners?
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