CBX2 and KRTAP2-4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CBX2	KRTAP2-4
Description		chromobox 2	keratin associated protein 2-4
Image			No pdb structure
GO Annotations	Cellular Component	Euchromatin Heterochromatin Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Cytosol Keratin Filament
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Methylated Histone Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Cell Differentiation Development Of Primary Sexual Characteristics	Keratinization
Pathways		Oxidative Stress Induced Senescence SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription	Keratinization Keratinization
Drugs
Diseases		46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS
Interacting Genes		15 interacting genes: DHX57 H3-4 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP2-4 KRTAP4-12 MDFI PCGF2 PHC2 RBMY1A1 RBMY1F RNF2 RYBP	11 interacting genes: ADAMTSL3 CBX2 CNNM3 KRTAP10-1 KRTAP10-5 PTPMT1 RPS28 SDC3 SHFL TMEM190 ZNF587
Entrez ID		84733	85294
HPRD ID		14397	13936
Ensembl ID		ENSG00000173894	ENSG00000213417
Uniprot IDs		Q14781	P0C7H8 Q9BYR9
PDB IDs		2D9U 3H91 5EPK
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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