ADRB1 and ARRB1

  • Number of citations of the paper that reports this interaction (PubMedID 18787115)
  • 96
  • Data Source:
  • BioGRID (pull down, affinity chromatography technology)
  • HPRD (in vitro)

ADRB1

ARRB1

Description adrenoceptor beta 1 arrestin beta 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Birth weight ( 23202124 31043758 27680694)
  • Blood pressure ( 21909110)
  • Diastolic blood pressure ( 28135244 27841878 28739976 27618452)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Gaucher disease severity ( 22388998)
  • High density lipoprotein cholesterol levels ( 29083408)
  • Lipid traits (pleiotropy) (HIPO component 1) ( 30289880)
  • Mean arterial pressure ( 27618448)
  • Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Offspring birth weight ( 31043758)
  • Systolic blood pressure ( 27841878 28739976 27618447 27618452 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Obstructive sleep apnea trait (average respiratory event duration) ( 26977737)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes 16 interacting genes: ADRA2A ARRB1 DLG1 DLG4 DLGAP2 GIPC1 GOPC GPRASP1 GPRASP2 GRB2 MAGI2 MAGI3 NOS1 SH3GL2 SH3GL3 SNTA1 54 interacting genes: ADH6 ADRB1 ADRB2 AGTR1 AP2B1 ARF6 BAG1 BTK C5AR1 CCR5 CDC42 CLTC CSK CXCR2 CYTH2 DVL1 DVL2 FGR FLNA GNB1 GNMT GPR50 GRK2 GSK3B HCK HCRTR1 JUN LIMK1 MAP2K3 MAP2K4 MAP3K5 MAPK1 MAPK10 MAPK3 MAPK9 MDM2 NEK6 NFKBIA NSF OPRD1 PDE4D PIK3R2 POT1 PRKN PTH1R PTHLH RALGDS RPL15 SASH1 SLC9A5 SREBF2 STAM TRHR ZBTB43
Entrez ID 153 408
HPRD ID 00181 00146
Ensembl ID ENSG00000043591 ENSG00000137486
Uniprot IDs P08588 B7Z1Q3 P49407
PDB IDs 2LSQ 2IV8
Enriched GO Terms of Interacting Partners?
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