CTNNA1 and CDH15

Number of citations of the paper that reports this interaction (PubMedID 9168809)
9

Data Source:
HPRD (in vitro)

		CTNNA1	CDH15
Description		catenin alpha 1	cadherin 15
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytosol Plasma Membrane Cell-cell Junction Zonula Adherens Focal Adhesion Intercalated Disc Actin Cytoskeleton Catenin Complex Flotillin Complex Lamellipodium Cell Junction Intracellular Membrane-bounded Organelle	Golgi Apparatus Plasma Membrane Caveola Adherens Junction Cell Surface Integral Component Of Membrane Catenin Complex Neuromuscular Junction Extracellular Exosome
	Molecular Function	RNA Binding Structural Molecule Activity Protein Binding Beta-catenin Binding Vinculin Binding Identical Protein Binding Gamma-catenin Binding Cadherin Binding Actin Filament Binding	Calcium Ion Binding Protein Binding Cytoskeletal Protein Binding Cadherin Binding
	Biological Process	Ovarian Follicle Development Cell Adhesion Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Neuroblast Proliferation Aging Male Gonad Development Gap Junction Assembly Axon Regeneration Adherens Junction Organization Cellular Protein Localization Odontogenesis Of Dentin-containing Tooth Apical Junction Assembly Response To Estrogen Positive Regulation Of Smoothened Signaling Pathway Positive Regulation Of Muscle Cell Differentiation Cellular Response To Indole-3-methanol Epithelial Cell-cell Adhesion Negative Regulation Of Cell Motility Negative Regulation Of Integrin-mediated Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Cell Morphogenesis Cell-cell Junction Assembly Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Multicellular Organism Development Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Muscle Cell Differentiation Cell-cell Adhesion
Pathways		Adherens junctions interactions VEGFR2 mediated vascular permeability Myogenesis Myogenesis RHO GTPases activate IQGAPs	Adherens junctions interactions Myogenesis Myogenesis
Drugs
Diseases			Non-syndromic autosomal dominant mental retardation
GWAS		General risk tolerance (MTAG) ( 30643258) Schizophrenia ( 25056061)
Interacting Genes		31 interacting genes: ACTN1 AFDN AJUBA APC APP ARMC8 CA9 CDH1 CDH15 CDH2 CDH3 CDH5 CSNK2A1 CTBP1 CTNNB1 DLG1 JUP LRATD2 MTNR1A MTNR1B OBI1 PKD1 PSEN1 SASH1 SPTAN1 SPTBN1 TJP1 TJP2 UBE2I VCL ZGPAT	10 interacting genes: ARVCF BOC CDH7 CDH9 CDON CTNNA1 CTNNB1 GNA12 JUP SGTA
Entrez ID		1495	1013
HPRD ID		00285	00225
Ensembl ID		ENSG00000044115	ENSG00000129910
Uniprot IDs		A0A384MDY0 B4DKT9 B4DU00 G3XAM7 P35221	P55291
PDB IDs		1H6G 4EHP 4IGG
Enriched GO Terms of Interacting Partners?
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