CTAG1B and HLA-DRB5

Number of citations of the paper that reports this interaction (PubMedID 11782380)
19

Data Source:
HPRD (in vitro)

		CTAG1B	HLA-DRB5
Description		cancer/testis antigen 1B	major histocompatibility complex, class II, DR beta 5
Image
GO Annotations	Cellular Component	Cytoplasm	Golgi Membrane Lysosomal Membrane Plasma Membrane ER To Golgi Transport Vesicle Membrane Transport Vesicle Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Late Endosome Membrane Trans-Golgi Network Membrane MHC Class II Protein Complex Extracellular Exosome Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Peptide Antigen Binding
	Biological Process	Positive Regulation Of Transcription By RNA Polymerase II TRNA Threonylcarbamoyladenosine Metabolic Process	Adaptive Immune Response Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II T Cell Receptor Signaling Pathway Interferon-gamma-mediated Signaling Pathway
Pathways			Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules MHC class II antigen presentation PD-1 signaling Interferon gamma signaling
Drugs
Diseases
GWAS			Acute anterior uveitis (with or without ankylosing spondylitis) ( 25200001) Alzheimer's disease ( 31473137) Alzheimer's disease (late onset) ( 30617256 24162737) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Antinuclear antibody levels ( 25186300) Asthma ( 30929738 27182965 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Automobile speeding propensity ( 30643258) Blood protein levels ( 29875488) Body mass index ( 28892062) Childhood ear infection ( 27182965) Chronic lymphocytic leukemia ( 21131588 26956414) Crohn's disease ( 23850713) Epstein Barr virus nuclear antigen 1 IgG levels ( 26819262) Frontotemporal dementia ( 24943344) Hand grip strength ( 29691431) Heart rate response to exercise ( 29769521) Hypothyroidism ( 22493691) Immune response to measles vaccine (measles-induced IFN gamma) ( 28289848) Inflammatory bowel disease ( 28067908) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Joint damage in rheumatoid arthritis ( 31596875) Lymphoma ( 23349640) Parkinson's disease ( 21292315 27182965) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Prostate cancer ( 23535732) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Sarcoidosis (non-Lofgren's syndrome) ( 26651848) SjÃ¶gren's syndrome ( 24097066) Tuberculosis ( 29036319) Type 2 diabetes ( 28869590) Ulcerative colitis ( 28067908 21297633 19122664) Vogt-Koyanagi-Harada syndrome ( 25108386) Waist-to-hip ratio adjusted for body mass index ( 26785701)
Interacting Genes		7 interacting genes: ATP6AP1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 MAGEC1 UBQLN1	2 interacting genes: CTAG1B HLA-DRA
Entrez ID		1485	3127
HPRD ID		02151	09209
Ensembl ID		ENSG00000184033	ENSG00000198502
Uniprot IDs		P78358	A0A2Z4LKS3 Q30154
PDB IDs		1S9W 2BNQ 2BNR 2F53 2F54 2P5E 2P5W 2PYE 3GJF 3HAE 3KLA 6AT5 6AVF 6AVG	1FV1 1H15 1HQR 1ZGL
Enriched GO Terms of Interacting Partners?
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