ADRA1A and ADRA1D

Number of citations of the paper that reports this interaction (PubMedID 15525470)
3

Data Source:
HPRD (two hybrid)

		ADRA1A	ADRA1D
Description		adrenoceptor alpha 1A	adrenoceptor alpha 1D
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Caveola Z Disc T-tubule Nuclear Membrane Dopaminergic Synapse Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane	Cell Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Adrenergic Receptor Activity Alpha1-adrenergic Receptor Activity Protein Binding Protein Heterodimerization Activity	Adrenergic Receptor Activity Alpha1-adrenergic Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Heart Rate Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Heart Rate By Epinephrine-norepinephrine Positive Regulation Of The Force Of Heart Contraction By Epinephrine-norepinephrine Positive Regulation Of Systemic Arterial Blood Pressure Apoptotic Process Smooth Muscle Contraction Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Adult Heart Development Aging Behavior Negative Regulation Of Cell Proliferation Response To Hormone Negative Regulation Of Autophagy Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Synaptic Transmission, GABAergic Negative Regulation Of Rho Protein Signal Transduction Intracellular Signal Transduction Response To Drug Positive Regulation Of MAPK Cascade Positive Regulation Of Action Potential Positive Regulation Of Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Micturition Calcium Ion Transport Into Cytosol Positive Regulation Of Cardiac Muscle Contraction Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of ERK1 And ERK2 Cascade Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Positive Regulation Of Protein Kinase C Signaling Pilomotor Reflex Positive Regulation Of Non-membrane Spanning Protein Tyrosine Kinase Activity Regulation Of Synaptic Vesicle Exocytosis	Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Behavior Positive Regulation Of Cell Proliferation Positive Regulation Of Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Pathways		Adrenoceptors G alpha (q) signalling events G alpha (12/13) signalling events	Adrenoceptors G alpha (q) signalling events G alpha (12/13) signalling events
Drugs		Amphetamine Midodrine Citalopram Ziprasidone Cabergoline Dapiprazole Amitriptyline Olanzapine Alfuzosin Clozapine Norepinephrine Mirtazapine Mirtazapine Phenylephrine Loxapine Promazine Dipivefrin Droperidol Prazosin Imipramine Chlorpromazine Chlorpromazine Nortriptyline Amoxapine Amoxapine Clonidine Doxazosin Labetalol Metaraminol Nicardipine Trazodone Verapamil Epinephrine Thioridazine Phentolamine Ergotamine Nicergoline Tamsulosin Methoxamine Trimipramine Risperidone Epinastine Propiomazine Tolazoline Fenoldopam Trifluoperazine Pseudoephedrine Benzphetamine Flupentixol Quinidine Phenoxybenzamine Maprotiline Oxymetazoline Apraclonidine Ergoloid mesylate Promethazine Carvedilol Doxepin Nefazodone Desipramine Terazosin Escitalopram Pergolide Bromocriptine Quetiapine Aripiprazole Ergonovine Paliperidone Bevantolol Ephedrine Mephentermine Methotrimeprazine 4-Methoxyamphetamine Dextroamphetamine Phendimetrazine Acepromazine Thioproperazine Zuclopenthixol Dronedarone Iloperidone R450 Epicept NP-1 Sertindole Mianserin Silodosin Asenapine Droxidopa Xylometazoline Isometheptene Naphazoline Tetryzoline Perospirone Indoramin Dosulepin Etoperidone Cirazoline Synephrine Niguldipine Tiapride	Amphetamine Midodrine Cabergoline Dapiprazole Amitriptyline Alfuzosin Norepinephrine Mirtazapine Phenylephrine Promazine Prazosin Imipramine Chlorpromazine Nortriptyline Amoxapine Clonidine Doxazosin Labetalol Nicardipine Verapamil Epinephrine Phentolamine Ergotamine Tamsulosin Methoxamine Propiomazine Fenoldopam Quinidine Phenoxybenzamine Maprotiline Oxymetazoline Ergoloid mesylate Carvedilol Doxepin Desipramine Terazosin Pergolide Bromocriptine Quetiapine Mephentermine Methotrimeprazine Dronedarone R450 Epicept NP-1 Sertindole Mianserin Silodosin Droxidopa Xylometazoline Perospirone Dosulepin Etoperidone Cirazoline Synephrine Tiapride
Diseases
GWAS		Blood metabolite levels ( 24816252) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Response to amphetamines ( 22952603) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)	Paneth cell defects in Crohn's disease ( 28352666) Preeclampsia ( 23551011) Sense of smell ( 26632684)
Interacting Genes		10 interacting genes: ABR ADRA1B ADRA1D BMP1 CXCR1 CXCR2 FLNC NOS1 PPP1R9B RGS2	8 interacting genes: ADRA1A FLNC LNX1 NOS1 SNTA1 SNTB1 SNTB2 SNTG1
Entrez ID		148	146
HPRD ID		00081	00079
Ensembl ID		ENSG00000120907	ENSG00000171873
Uniprot IDs		B0ZBD3 P35348	B0ZBE0 P25100
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?