SENP8 and UBE2M

Number of citations of the paper that reports this interaction (PubMedID 28475037)
11

		SENP8	UBE2M
Description		SUMO peptidase family member, NEDD8 specific	ubiquitin conjugating enzyme E2 M
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GO Annotations	Cellular Component	Cytosol	Nucleoplasm Cytosol
	Molecular Function	NEDD8-specific Protease Activity	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding NEDD8 Transferase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Deubiquitination Post-translational Protein Modification	Cellular Protein Modification Process Protein Ubiquitination Positive Regulation Of Neuron Apoptotic Process Post-translational Protein Modification Protein Neddylation
Pathways		UCH proteinases Neddylation	TGF-beta receptor signaling activates SMADs Dectin-1 mediated noncanonical NF-kB signaling NIK - noncanonical NF-kB signaling Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Metabolite levels (HVA/MHPG ratio) ( 23319000)
Interacting Genes		13 interacting genes: COPS2 CUL1 CUL2 CUL4A GPS1 NEDD8 PLA2G2A SMURF1 TERF1 UBE2M USP15 USP21 USP28	28 interacting genes: APP CAND1 CBL CPNE1 CPNE2 CPNE4 CUL1 CUL7 DCUN1D1 DCUN1D2 DCUN1D3 DCUN1D4 DCUN1D5 FBXO7 ITCH MARCHF7 NEDD4 NEDD8 PINK1 PRKN RBX1 RNF111 RNF7 SENP8 SMURF1 TERF1 TP53 UBA3
Entrez ID		123228	9040
HPRD ID		09784	04414
Ensembl ID		ENSG00000166192	ENSG00000130725
Uniprot IDs		A8K8D3 Q96LD8	A0A024R4T4 P61081
PDB IDs		1XT9 2BKQ 2BKR	1TT5 1Y8X 2NVU 3TDU 3TDZ 4GAO 4P5O
Enriched GO Terms of Interacting Partners?
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