CKS1B and ROPN1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CKS1B	ROPN1
Description		CDC28 protein kinase regulatory subunit 1B	rhophilin associated tail protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleoplasm SCF Ubiquitin Ligase Complex	Nucleus Cytoplasm Motile Cilium
	Molecular Function	Protein Binding Protein Kinase Binding Histone Binding Ubiquitin Binding Cyclin-dependent Protein Serine/threonine Kinase Activator Activity	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Mitotic Cell Cycle Cell Proliferation Mitotic Cell Cycle Phase Transition Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Division	Regulation Of Protein Phosphorylation Flagellated Sperm Motility Cilium Organization Sperm Capacitation Protein Localization To Cilium
Pathways		SCF(Skp2)-mediated degradation of p27/p21 Cyclin D associated events in G1	RHO GTPases Activate Rhotekin and Rhophilins
Drugs		Fluoxetine Meta Vanadate
Diseases
GWAS		Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Prostate cancer ( 23535732)	Household income ( 31844048) Household income (MTAG) ( 31844048)
Interacting Genes		32 interacting genes: AP2M1 ARID5A CBY2 CCNA1 CCNB2 CDC27 CDC37 CDK2 CDKN1B CDX4 CKS1BP7 CKS2 CUL1 DUSP1 ECPAS HSP90AA1 IKZF1 KRTAP10-9 KRTAP5-9 LDHB MEOX1 MIPOL1 PSMD9 REL ROPN1 SEPTIN3 SKP2 SSBP1 SUMO1P1 TCF4 TRIM27 XIAP	26 interacting genes: AKAP3 AKAP7 CEP57L1 CKS1B CNST FAM162A GNL3L GPKOW HNRNPUL1 KIF9 LENG1 LNX1 LNX2 NTAQ1 POLR3C PRKAA1 PSMA1 RHPN1 RTP5 SDCBP SERTAD1 SPA17 TSNAXIP1 TULP3 UBE2W XKR3
Entrez ID		1163	54763
HPRD ID		00299	15269
Ensembl ID		ENSG00000173207	ENSG00000065371
Uniprot IDs		P61024 Q5T178	A0A140VKB2 Q9HAT0
PDB IDs		1BUH 1DKS 1DKT 2ASS 2AST 4YC6
Enriched GO Terms of Interacting Partners?
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