CMTM5 and CPLX1

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		CMTM5	CPLX1
Description		CKLF like MARVEL transmembrane domain containing 5	complexin 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Integral Component Of Membrane	Cytosol Cell Junction Dendrite SNARE Complex Terminal Bouton Perikaryon Calyx Of Held Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-3-complexin Complex Schaffer Collateral - CA1 Synapse Postsynapse Glutamatergic Synapse
	Molecular Function	Cytokine Activity Protein Binding	SNARE Binding Neurotransmitter Transporter Activity Protein Binding Syntaxin-1 Binding
	Biological Process	Chemotaxis Signal Transduction Negative Regulation Of Myoblast Differentiation	Exocytosis Chemical Synaptic Transmission Neurotransmitter Secretion Glutamate Secretion Synaptic Vesicle Exocytosis Regulation Of Exocytosis Insulin Secretion Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Regulation Of Neurotransmitter Secretion Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane
Pathways			Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation
Drugs
Diseases
GWAS			Heel bone mineral density ( 30598549)
Interacting Genes		54 interacting genes: AACS ACSF2 ALDH18A1 APOA1 ARMC9 COQ8A CPLX1 CREB3 CYP1A1 DDA1 ECPAS FAM114A1 FARS2 FERMT2 GAD1 GAD2 GLTP GOLGA2P10 GTF3C1 HNRNPK LMNA LMO2 MCEE MTERF3 MYG1 NDRG4 PIMREG PITPNC1 PLIN3 PNPO PPIF PPP2R3C PTPN9 RBFA RMDN2 RNF185 RSRC2 SDCBP SH3GLB1 SHMT2 SNX1 SPATA8 SPG21 SSX3 SUCLA2 SYNE4 TIMM44 TPD52L3 TTPA TUBB TUFM VARS2 ZNF391 ZNF599	5 interacting genes: AGTRAP CMTM5 SNAP25 STX1A VAMP2
Entrez ID		116173	10815
HPRD ID		06986	09233
Ensembl ID		ENSG00000166091	ENSG00000168993
Uniprot IDs		Q96DZ9	O14810
PDB IDs			3RK3 3RL0
Enriched GO Terms of Interacting Partners?
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