CPLX1 and CMTM5

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		CPLX1	CMTM5
Description		complexin 1	CKLF like MARVEL transmembrane domain containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cell Junction Dendrite SNARE Complex Terminal Bouton Perikaryon Calyx Of Held Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-3-complexin Complex Schaffer Collateral - CA1 Synapse Postsynapse Glutamatergic Synapse	Extracellular Space Integral Component Of Membrane
	Molecular Function	SNARE Binding Neurotransmitter Transporter Activity Protein Binding Syntaxin-1 Binding	Cytokine Activity Protein Binding
	Biological Process	Exocytosis Chemical Synaptic Transmission Neurotransmitter Secretion Glutamate Secretion Synaptic Vesicle Exocytosis Regulation Of Exocytosis Insulin Secretion Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Regulation Of Neurotransmitter Secretion Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane	Chemotaxis Signal Transduction Negative Regulation Of Myoblast Differentiation
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549)
Interacting Genes		5 interacting genes: AGTRAP CMTM5 SNAP25 STX1A VAMP2	54 interacting genes: AACS ACSF2 ALDH18A1 APOA1 ARMC9 COQ8A CPLX1 CREB3 CYP1A1 DDA1 ECPAS FAM114A1 FARS2 FERMT2 GAD1 GAD2 GLTP GOLGA2P10 GTF3C1 HNRNPK LMNA LMO2 MCEE MTERF3 MYG1 NDRG4 PIMREG PITPNC1 PLIN3 PNPO PPIF PPP2R3C PTPN9 RBFA RMDN2 RNF185 RSRC2 SDCBP SH3GLB1 SHMT2 SNX1 SPATA8 SPG21 SSX3 SUCLA2 SYNE4 TIMM44 TPD52L3 TTPA TUBB TUFM VARS2 ZNF391 ZNF599
Entrez ID		10815	116173
HPRD ID		09233	06986
Ensembl ID		ENSG00000168993	ENSG00000166091
Uniprot IDs		O14810	Q96DZ9
PDB IDs		3RK3 3RL0
Enriched GO Terms of Interacting Partners?
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