CISH and MAP3K7CL

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CISH	MAP3K7CL
Description		cytokine inducible SH2 containing protein	MAP3K7 C-terminal like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol Plasma Membrane Phosphatidylinositol 3-kinase Complex	Nucleus Cytosol
	Molecular Function	Molecular_function Protein Binding 1-phosphatidylinositol-3-kinase Regulator Activity	Protein Binding
	Biological Process	Regulation Of Cell Growth Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Protein Ubiquitination Intracellular Signal Transduction Interleukin-7-mediated Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase Activity Post-translational Protein Modification Phosphatidylinositol Phosphorylation
Pathways		Interleukin-7 signaling Neddylation Growth hormone receptor signaling
Drugs
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025)	Coronary artery disease ( 29212778) Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect) ( 30920136) Gamma glutamyl transferase levels ( 29403010) Ventricular ectopy ( 29618737)
Interacting Genes		18 interacting genes: CSF2RB CSF3R EPOR ERBB2 ETV5 GHR GPX1 HSPA6 IL2RB IL3RA KIT MAP3K7CL MYD88 PRKCA PRKCB PRKCQ PRLR SMAD2	6 interacting genes: AK8 CISH GPS2 KRT31 REL TAB3
Entrez ID		1154	56911
HPRD ID		03897	10764
Ensembl ID		ENSG00000114737	ENSG00000156265
Uniprot IDs		Q9NSE2	B0EVZ6 B0EVZ7 B0EVZ8 B4DFW0 P57077
PDB IDs
Enriched GO Terms of Interacting Partners?
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