USP18 and TMEM14A

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

		USP18	TMEM14A
Description		ubiquitin specific peptidase 18	transmembrane protein 14A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Thiol-dependent Ubiquitinyl Hydrolase Activity	Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination Regulation Of Inflammatory Response Regulation Of Type I Interferon-mediated Signaling Pathway	Mitochondrial Transport Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Pathways		ISG15 antiviral mechanism Ub-specific processing proteases Regulation of IFNA signaling
Drugs
Diseases
GWAS			Metabolite levels ( 23823483) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Response to hepatitis B vaccine ( 29534301)
Interacting Genes		5 interacting genes: IFNAR2 ISG15 TMEM14A TRIM54 ZDHHC17	7 interacting genes: CLN8 CREB3 LMNA LXN MTNR1A MTNR1B USP18
Entrez ID		11274	28978
HPRD ID		06136	15522
Ensembl ID		ENSG00000184979	ENSG00000096092
Uniprot IDs		Q9UMW8	Q9Y6G1
PDB IDs			2LOO 2LOP
Enriched GO Terms of Interacting Partners?
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