NUDT21 and HSF4

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		NUDT21	HSF4
Description		nudix hydrolase 21	heat shock transcription factor 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA Cleavage Factor Complex Nuclear Body Centriolar Satellite Paraspeckles	Nuclear Chromatin Nucleus Nuclear Speck
	Molecular Function	Chromatin Binding RNA Binding MRNA Binding Protein Binding Hydrolase Activity AU-rich Element Binding MRNA 3'-UTR AU-rich Region Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Corepressor Activity Identical Protein Binding Sequence-specific DNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Processing Posttranscriptional Regulation Of Gene Expression Cell Differentiation MRNA 3'-end Processing Positive Regulation Of MRNA Cleavage Protein Tetramerization Protein Heterotetramerization Pre-mRNA Cleavage Required For Polyadenylation MRNA Alternative Polyadenylation Positive Regulation Of MRNA Polyadenylation Messenger Ribonucleoprotein Complex Assembly Positive Regulation Of Stem Cell Differentiation Positive Regulation Of Pro-B Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Visual Perception Positive Regulation Of Cell Proliferation Histone H3-K9 Demethylation Cellular Response To Heat Camera-type Eye Development Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Cell Differentiation Cell Development Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Heat Stress
Pathways		mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
Interacting Genes		51 interacting genes: A2M ATXN1 CARM1 CEP126 CLP1 CPSF6 CPSF7 CTNND2 DBN1 DNMT3L DYNC1I1 EED EEF1G ESR1 EXOSC6 F13A1 FBN3 FLAD1 FUNDC2 GOLGA2 HSF4 IKZF1 ITCH JMJD1C KIFAP3 MASP1 MYL6 NEDD4 NGEF NIF3L1 POLR2C PSMF1 PTN PYCR1 RBM48 RCC1 RNF19A RPLP1 SEM1 SEMA5B SF3B1 SHC1 SLC44A1 SNCAIP SNRNP70 SRPK1 TCERG1 TLE1 TRA2A TRIM27 WWOX	13 interacting genes: ALKBH4 CDK2AP2 DAXX DUSP26 MAPK1 MAPK14 MAPK3 MAPK8 NUDT21 SLC27A5 SMARCA4 STOML2 ZBED8
Entrez ID		11051	3299
HPRD ID		05400	03896
Ensembl ID		ENSG00000167005	ENSG00000102878
Uniprot IDs		A0A024R6W2 O43809	A0A024R6X7 Q9ULV5
PDB IDs		2CL3 2J8Q 3BAP 3BHO 3MDG 3MDI 3N9U 3P5T 3P6Y 3Q2S 3Q2T
Enriched GO Terms of Interacting Partners?
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