HSF4 and ALKBH4

Number of citations of the paper that reports this interaction (PubMedID 23145062)
8

Data Source:
BioGRID (two hybrid)

		HSF4	ALKBH4
Description		heat shock transcription factor 4	alkB homolog 4, lysine demethylase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nuclear Speck	Nucleolus Cytoplasm Midbody Contractile Ring
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Corepressor Activity Identical Protein Binding Sequence-specific DNA Binding	Actin Binding Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, 2-oxoglutarate As One Donor, And Incorporation Of One Atom Each Of Oxygen Into Both Donors Demethylase Activity Oxidative DNA Demethylase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Visual Perception Positive Regulation Of Cell Proliferation Histone H3-K9 Demethylation Cellular Response To Heat Camera-type Eye Development Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Cell Differentiation Cell Development Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Heat Stress	Chromatin Organization Protein Demethylation Actomyosin Structure Organization Oxidative DNA Demethylation Cleavage Furrow Ingression Oxidative Demethylation DNA Demethylation Regulation Of Chromatin Organization
Pathways
Drugs
Diseases
GWAS			Morning person ( 30696823)
Interacting Genes		13 interacting genes: ALKBH4 CDK2AP2 DAXX DUSP26 MAPK1 MAPK14 MAPK3 MAPK8 NUDT21 SLC27A5 SMARCA4 STOML2 ZBED8	12 interacting genes: DTX2 EIF3C EP300 HSF4 MEPCE MLLT1 MLLT3 MTMR6 PSMA6 TES TRAF4 ZFHX3
Entrez ID		3299	54784
HPRD ID		03896	07875
Ensembl ID		ENSG00000102878	ENSG00000160993
Uniprot IDs		A0A024R6X7 Q9ULV5	Q9NXW9
PDB IDs
Enriched GO Terms of Interacting Partners?
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