WASF3 and ACTR3

Number of citations of the paper that reports this interaction (PubMedID 10381382)
67

Data Source:
HPRD (in vivo)

		WASF3	ACTR3
Description		WASP family member 3	actin related protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Lamellipodium Extracellular Exosome Postsynapse Glutamatergic Synapse	Cell Nucleus Cytoplasm Cytosol Arp2/3 Protein Complex Brush Border Cell-cell Junction Focal Adhesion Actin Cytoskeleton Membrane Lamellipodium Actin Cortical Patch Site Of Double-strand Break Extracellular Exosome
	Molecular Function	Actin Binding	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Actin Filament Binding
	Biological Process	Cytoskeleton Organization Regulation Of Cell Shape Oligodendrocyte Development Lamellipodium Assembly Actin Filament Polymerization Positive Regulation Of Myelination Protein-containing Complex Assembly Modification Of Postsynaptic Actin Cytoskeleton	Establishment Or Maintenance Of Cell Polarity Asymmetric Cell Division Meiotic Chromosome Movement Towards Spindle Pole Meiotic Cytokinesis Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Transcription By RNA Polymerase II Ephrin Receptor Signaling Pathway Spindle Localization Cilium Assembly Membrane Organization Actin Polymerization-dependent Cell Motility Cellular Response To Interferon-gamma
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs			N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS		Metabolite levels ( 23823483) Sporadic pituitary adenoma ( 26029870) Systolic blood pressure ( 30224653)	Metabolite levels ( 23823483) Systolic blood pressure in sickle cell anemia ( 24058526)
Interacting Genes		6 interacting genes: ACTB ACTR3 CAMK2D EGFR PIK3R1 PIK3R2	16 interacting genes: ACTR2 ARPC2 ARPC3 ARPC4 ARPC5 CDC42 CDH1 CTTN HCLS1 JUND SHARPIN UBE3A WASF1 WASF2 WASF3 WASL
Entrez ID		10810	10096
HPRD ID		05458	05024
Ensembl ID		ENSG00000132970	ENSG00000115091
Uniprot IDs		Q5T8P4 Q9UPY6	A0A024RAI1 B4DXW1 P61158
PDB IDs
Enriched GO Terms of Interacting Partners?
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