ACTR3 and WASF3

Number of citations of the paper that reports this interaction (PubMedID 10381382)
67

Data Source:
HPRD (in vivo)

		ACTR3	WASF3
Description		actin related protein 3	WASP family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Cytoplasm Cytosol Arp2/3 Protein Complex Brush Border Cell-cell Junction Focal Adhesion Actin Cytoskeleton Membrane Lamellipodium Actin Cortical Patch Site Of Double-strand Break Extracellular Exosome	Cytoplasm Cytoskeleton Lamellipodium Extracellular Exosome Postsynapse Glutamatergic Synapse
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Actin Filament Binding	Actin Binding
	Biological Process	Establishment Or Maintenance Of Cell Polarity Asymmetric Cell Division Meiotic Chromosome Movement Towards Spindle Pole Meiotic Cytokinesis Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Transcription By RNA Polymerase II Ephrin Receptor Signaling Pathway Spindle Localization Cilium Assembly Membrane Organization Actin Polymerization-dependent Cell Motility Cellular Response To Interferon-gamma	Cytoskeleton Organization Regulation Of Cell Shape Oligodendrocyte Development Lamellipodium Assembly Actin Filament Polymerization Positive Regulation Of Myelination Protein-containing Complex Assembly Modification Of Postsynaptic Actin Cytoskeleton
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs		N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS		Metabolite levels ( 23823483) Systolic blood pressure in sickle cell anemia ( 24058526)	Metabolite levels ( 23823483) Sporadic pituitary adenoma ( 26029870) Systolic blood pressure ( 30224653)
Interacting Genes		16 interacting genes: ACTR2 ARPC2 ARPC3 ARPC4 ARPC5 CDC42 CDH1 CTTN HCLS1 JUND SHARPIN UBE3A WASF1 WASF2 WASF3 WASL	6 interacting genes: ACTB ACTR3 CAMK2D EGFR PIK3R1 PIK3R2
Entrez ID		10096	10810
HPRD ID		05024	05458
Ensembl ID		ENSG00000115091	ENSG00000132970
Uniprot IDs		A0A024RAI1 B4DXW1 P61158	Q5T8P4 Q9UPY6
PDB IDs
Enriched GO Terms of Interacting Partners?
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