AHCYL1 and SLC23A1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AHCYL1	SLC23A1
Description		adenosylhomocysteinase like 1	solute carrier family 23 member 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Apical Plasma Membrane Extracellular Exosome	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Membrane Apical Plasma Membrane Intracellular Organelle Extracellular Exosome
	Molecular Function	RNA Binding Adenosylhomocysteinase Activity Protein Binding Identical Protein Binding	Transporter Activity Protein Binding L-ascorbate:sodium Symporter Activity Sodium Ion Transmembrane Transporter Activity Nucleobase Transmembrane Transporter Activity L-ascorbic Acid Transmembrane Transporter Activity Dehydroascorbic Acid Transmembrane Transporter Activity Sodium-dependent L-ascorbate Transmembrane Transporter Activity
	Biological Process	MRNA Polyadenylation Protein Export From Nucleus One-carbon Metabolic Process Positive Regulation Of Sodium Ion Transport Regulation Of MRNA 3'-end Processing Regulation Of Ion Transmembrane Transporter Activity S-adenosylmethionine Cycle Angiotensin-activated Signaling Pathway Epithelial Fluid Transport Regulation Of Anion Transport Response To Calcium Ion Regulation Of Cardiac Conduction	Nucleobase-containing Compound Metabolic Process Sodium Ion Transport Brain Development Response To Toxic Substance Nucleobase Transport L-ascorbic Acid Transmembrane Transport L-ascorbic Acid Metabolic Process Lung Development Sodium Ion Transmembrane Transport Dehydroascorbic Acid Transport Transepithelial L-ascorbic Acid Transport
Pathways		PLC beta mediated events DAG and IP3 signaling Role of phospholipids in phagocytosis FCERI mediated Ca+2 mobilization Regulation of insulin secretion VEGFR2 mediated cell proliferation Ion homeostasis Ion homeostasis CLEC7A (Dectin-1) induces NFAT activation FCGR3A-mediated IL10 synthesis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	Vitamin C (ascorbate) metabolism
Drugs			Vitamin C
Diseases
GWAS		Height ( 31562340)	Body mass index ( 26426971)
Interacting Genes		17 interacting genes: BID CDKN2C DACH1 GEM HGS ITPR1 LRRK2 MEOX2 MFHAS1 PPL PSMD9 RNF6 SLC23A1 SOX30 SRPK1 SRPK2 ZNF165	12 interacting genes: ADAMTSL4 AHCYL1 KRT31 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 MTUS2 NOTCH2NLA
Entrez ID		10768	9963
HPRD ID		07613	04810
Ensembl ID		ENSG00000168710	ENSG00000170482
Uniprot IDs		A0A024R0A8 O43865	Q9UHI7
PDB IDs		3MTG
Enriched GO Terms of Interacting Partners?
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