AHCYL1 and SOX30

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AHCYL1	SOX30
Description		adenosylhomocysteinase like 1	SRY-box transcription factor 30
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Apical Plasma Membrane Extracellular Exosome	Nuclear Chromatin Nucleus Cytoplasm Chromocenter
	Molecular Function	RNA Binding Adenosylhomocysteinase Activity Protein Binding Identical Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Beta-catenin Binding Sequence-specific DNA Binding
	Biological Process	MRNA Polyadenylation Protein Export From Nucleus One-carbon Metabolic Process Positive Regulation Of Sodium Ion Transport Regulation Of MRNA 3'-end Processing Regulation Of Ion Transmembrane Transporter Activity S-adenosylmethionine Cycle Angiotensin-activated Signaling Pathway Epithelial Fluid Transport Regulation Of Anion Transport Response To Calcium Ion Regulation Of Cardiac Conduction	Negative Regulation Of Transcription By RNA Polymerase II Spermatid Development Negative Regulation Of Wnt Signaling Pathway Response To Corticosteroid Positive Regulation Of Transcription By RNA Polymerase II
Pathways		PLC beta mediated events DAG and IP3 signaling Role of phospholipids in phagocytosis FCERI mediated Ca+2 mobilization Regulation of insulin secretion VEGFR2 mediated cell proliferation Ion homeostasis Ion homeostasis CLEC7A (Dectin-1) induces NFAT activation FCGR3A-mediated IL10 synthesis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
GWAS		Height ( 31562340)	Glycated hemoglobin levels ( 28898252) Triglyceride levels ( 31647587)
Interacting Genes		17 interacting genes: BID CDKN2C DACH1 GEM HGS ITPR1 LRRK2 MEOX2 MFHAS1 PPL PSMD9 RNF6 SLC23A1 SOX30 SRPK1 SRPK2 ZNF165	18 interacting genes: AHCYL1 AURKA BAMBI BRCA1 CFAP206 CUL5 DCAF4 DDX56 FBXO38 FLI1 GNAI3 GP2 KIFC3 MRPS5 NME1 NUDT3 PAXIP1 TRAF2
Entrez ID		10768	11063
HPRD ID		07613	09461
Ensembl ID		ENSG00000168710	ENSG00000039600
Uniprot IDs		A0A024R0A8 O43865	B4DXW7 O94993
PDB IDs		3MTG
Enriched GO Terms of Interacting Partners?
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