GIPC1 and CARD10

Number of citations of the paper that reports this interaction (PubMedID 29467281)
4

Data Source:
BioGRID (two hybrid)

		GIPC1	CARD10
Description		GIPC PDZ domain containing family member 1	caspase recruitment domain family member 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Brush Border Cell Cortex Synaptic Vesicle Vesicle Membrane Membrane Endocytic Vesicle Cytoplasmic Vesicle Dendritic Spine Dendritic Shaft Extracellular Exosome Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Cytoplasm CBM Complex
	Molecular Function	Actin Binding Signaling Receptor Binding Protein Binding Myosin Binding PDZ Domain Binding Identical Protein Binding Cadherin Binding	Protein Binding Receptor Signaling Complex Scaffold Activity CARD Domain Binding
	Biological Process	Protein Targeting G Protein-coupled Receptor Signaling Pathway Chemical Synaptic Transmission Glutamate Secretion Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Stability Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cytokinesis Endothelial Cell Migration Positive Regulation Of Melanin Biosynthetic Process Regulation Of Synaptic Plasticity Cellular Response To Interleukin-7 Regulation Of Synaptic Vesicle Exocytosis	Activation Of NF-kappaB-inducing Kinase Activity Regulation Of Apoptotic Process Protein-containing Complex Assembly Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases
GWAS		Kidney stones ( 31729369)	Autoimmune hepatitis type-1 ( 24768677) Low vWF levels ( 26486471) Optic disc area ( 25631615 31798171 28073927 21307088) Optic disc size ( 31809533) Vertical cup-disc ratio ( 25241763 28073927) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		37 interacting genes: ACTN1 ADRB1 ARHGEF12 BRD4 CARD10 CD93 DDIT3 DRD2 DRD3 FZD3 GSK3B IGF1R ITGA5 ITGA6 KIF1B LHCGR LPAR1 LPAR2 LRP1 LRP2 LRP8 MYO6 NRP1 NTRK1 NTRK2 RGS1 RGS19 SDC4 SEMA4B SEMA4C SH3BP4 SLC2A1 TGFBR3 TPBG TYRP1 ZFPM1 ZNF408	6 interacting genes: ATXN7 BCL10 GIPC1 IKBKG KLHL12 TMEM43
Entrez ID		10755	29775
HPRD ID		05462	06233
Ensembl ID		ENSG00000123159	ENSG00000100065
Uniprot IDs		A0A024R7I0 A0A024R7I1 A8K2I7 O14908	Q9BWT7
PDB IDs
Enriched GO Terms of Interacting Partners?
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