SMC2 and DNMT3B

  • Number of citations of the paper that reports this interaction (PubMedID 15148359)
  • 46
  • Data Source:
  • BioGRID (biochemical, pull down)

SMC2

DNMT3B

Description structural maintenance of chromosomes 2 DNA methyltransferase 3 beta
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Basal cell carcinoma ( 31174203)
  • Keratinocyte cancer (MTAG) ( 31174203)
  • Orofacial clefts (maternal alcohol consumption interaction) ( 21618603)
  • Pancreatic cancer ( 29422604)
  • Pancreatic ductal adenocarcinoma ( 30541042)
  • Sensorimotor dexterity ( 31596458)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Inflammatory bowel disease ( 23128233)
  • Iron status biomarkers (iron levels) ( 28334935)
  • Lymphocyte counts ( 27863252)
  • Lymphocyte percentage of white cells ( 27863252)
  • Nicotine dependence ( 28972577)
  • Prostate cancer ( 29892016)
  • Pulse pressure ( 27841878 30578418)
  • Total cholesterol levels ( 30275531)
Interacting Genes 9 interacting genes: ABCC5 DISC1 DNMT3B ERP44 GULP1 LIG4 NCAPD2 SMC4 TRAF3IP1 38 interacting genes: BAZ2A CBX1 CBX3 CBX5 CMTM6 CUL4B DDB1 DNMT1 DNMT3A DNMT3L DUSP23 EED EZH2 H3C1 HDAC1 HDAC2 HELLS KIF4A MAP1LC3B MBD4 NCAPG NEDD8 NRIP1 PAM16 PCYT2 PLEKHJ1 RPS10 SMARCA5 SMC2 SPI1 SUMO1 SUV39H1 TDG TSC22D1 UBE2I UBE2W WARS1 ZBTB18
Entrez ID 10592 1789
HPRD ID 09277 04209
Ensembl ID ENSG00000136824 ENSG00000088305
Uniprot IDs A0A024R158 A8K984 B3KMB1 B7ZLZ7 O95347 Q05BV1 Q05D74 Q6IPS5 Q7Z2X1 Q9UBC3
PDB IDs 4U4P 3FLG 3QKJ 5CIU 5NR3 5NRR 5NRS 5NRV 5NV0 5NV2 5NV7 5NVO
Enriched GO Terms of Interacting Partners?
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