SMC2 and ABCC5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		SMC2	ABCC5
Description		structural maintenance of chromosomes 2	ATP binding cassette subfamily C member 5
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Condensed Chromosome Condensin Complex Condensin Core Heterodimer Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Membrane Basolateral Plasma Membrane
	Molecular Function	Single-stranded DNA Binding Protein Binding ATP Binding	ATP Binding Organic Anion Transmembrane Transporter Activity Efflux Transmembrane Transporter Activity ATPase Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances Xenobiotic Transmembrane Transporter Activity
	Biological Process	Mitotic Chromosome Condensation Meiotic Chromosome Condensation Meiotic Chromosome Segregation Cell Division Kinetochore Organization	Organic Anion Transport Hyaluronan Biosynthetic Process Xenobiotic Transport Transmembrane Transport Export Across Plasma Membrane
Pathways		Condensation of Prophase Chromosomes Condensation of Prometaphase Chromosomes Condensation of Prometaphase Chromosomes	Hyaluronan biosynthesis and export ABC-family proteins mediated transport
Drugs			Curcumin
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Basal cell carcinoma ( 31174203) Keratinocyte cancer (MTAG) ( 31174203) Orofacial clefts (maternal alcohol consumption interaction) ( 21618603) Pancreatic cancer ( 29422604) Pancreatic ductal adenocarcinoma ( 30541042) Sensorimotor dexterity ( 31596458)	Anterior chamber depth ( 24603532) Platelet count ( 27863252) Type 2 diabetes ( 30297969)
Interacting Genes		9 interacting genes: ABCC5 DISC1 DNMT3B ERP44 GULP1 LIG4 NCAPD2 SMC4 TRAF3IP1	4 interacting genes: AK2 RBP5 SERPINA3 SMC2
Entrez ID		10592	10057
HPRD ID		09277	06898
Ensembl ID		ENSG00000136824	ENSG00000114770
Uniprot IDs		A0A024R158 A8K984 B3KMB1 B7ZLZ7 O95347 Q05BV1 Q05D74 Q6IPS5 Q7Z2X1	O15440
PDB IDs		4U4P
Enriched GO Terms of Interacting Partners?
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