HMG20A and PHF21A

Number of citations of the paper that reports this interaction (PubMedID 26496610)
285

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down)

		HMG20A	PHF21A
Description		high mobility group 20A	PHD finger protein 21A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Histone Deacetylase Complex Nucleoplasm DNA Repair Complex
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding	DNA Binding Chromatin Binding Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Negative Regulation Of Neuron Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Blood Coagulation
Pathways			HDACs deacetylate histones Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Hand grip strength ( 29691431) Hemoglobin A1c levels ( 29403010) Medication use (drugs used in diabetes) ( 31015401) Type 2 diabetes ( 21490949 22885922 24509480 30054458 22693455 21874001 30297969 30718926 28869590)	Adventurousness ( 30643258) Axial length ( 24144296) Height ( 29782485) Menarche (age at onset) ( 21102462 25231870) Urate levels ( 31578528)
Interacting Genes		25 interacting genes: ADD1 BRAP CCDC136 CCNK CFAP53 DCTN4 DTNA DTNB FBXO7 FMNL1 GTF2A1L HMG20B HPCAL1 KPNA2 MAGOHB PHF21A PSTPIP1 PTH2R RBM7 RPP30 RSPH9 SCNM1 SMAD4 SYTL4 TESC	14 interacting genes: BANP FHL3 H3C14 HDAC1 HDAC2 HMG20A HMG20B KDM1A KRT40 LPXN NUP62 RCOR1 TRAF1 ZYX
Entrez ID		10363	51317
HPRD ID		16116	10516
Ensembl ID		ENSG00000140382	ENSG00000135365
Uniprot IDs		B4DMG1 Q9NP66	Q96BD5
PDB IDs			2PUY 2YQL
Enriched GO Terms of Interacting Partners?
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