SIGMAR1 and DNAJB5

		SIGMAR1	DNAJB5
Description		sigma non-opioid intracellular receptor 1	DnaJ heat shock protein family (Hsp40) member B5
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Integral Component Of Plasma Membrane Postsynaptic Density Integral Component Of Membrane Cell Junction Growth Cone Cytoplasmic Vesicle Postsynaptic Density Membrane	Nucleus Cytosol
	Molecular Function	Opioid Receptor Activity Protein Binding Drug Binding	Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Lipid Transport Nervous System Development Cell Death In Response To Hydrogen Peroxide Opioid Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process Protein Homotrimerization	Negative Regulation Of Transcription By RNA Polymerase II Response To Unfolded Protein Chaperone Cofactor-dependent Protein Refolding
Pathways
Drugs		Amitriptyline Remoxipride Dextromethorphan Nortriptyline Pentazocine Cocaine Dimethyltryptamine Prasterone Phencyclidine Captodiame
Diseases
GWAS			Response to quetiapine in schizophrenia ( 29503163)
Interacting Genes		13 interacting genes: ANK2 DCAF12 DNAJB5 GNE ITPR3 NFX1 PDZD11 PHF24 RECK RUSC2 SPAG8 SPINK4 VCP	3 interacting genes: CACNA1A SIGMAR1 TBPL2
Entrez ID		10280	25822
HPRD ID		03580	07106
Ensembl ID		ENSG00000147955	ENSG00000137094
Uniprot IDs		A2A3U5 B4DR71 Q99720	O75953
PDB IDs		5HK1 5HK2 6DJZ 6DK0 6DK1
Enriched GO Terms of Interacting Partners?
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