CD96 and PVR

Number of citations of the paper that reports this interaction (PubMedID 19056733)
19

Data Source:
HPRD (in vitro)

		CD96	PVR
Description		CD96 molecule	PVR cell adhesion molecule
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Space Cytoplasm Plasma Membrane Adherens Junction Focal Adhesion Cell Surface Integral Component Of Membrane
	Molecular Function		Virus Receptor Activity Protein Binding Signaling Receptor Activity Protein Homodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Cytokine Production Involved In Inflammatory Response Negative Regulation Of Natural Killer Cell Cytokine Production Immune Response Cell Adhesion Cell-matrix Adhesion Response To Lipopolysaccharide Negative Regulation Of Interferon-gamma Production Regulation Of Immune Response	Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Viral Entry Into Host Cell Regulation Of Immune Response Susceptibility To T Cell Mediated Cytotoxicity
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Nectin/Necl trans heterodimerization
Drugs			Sphingosine Myristic acid
Diseases		C syndrome, including: Opitz trigonocephaly syndrome; Bohring-Opitz syndrome (BOPS)
GWAS		Anti-adalimumab antibody production in response to treatment in Crohn's disease ( 31043678) Current cigarettes per day in chronic obstructive pulmonary disease ( 21685187)	Alzheimer's disease ( 24755620) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Mean platelet volume ( 27863252) Multiple sclerosis ( 21833088) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376)
Interacting Genes		1 interacting genes: PVR	25 interacting genes: AP1M2 CD226 CD96 DMPK DYNLT1 DYNLT3 GMEB2 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 NECTIN1 NECTIN2 NECTIN3 NOTCH2NLA PLA2G3 PLAT PSG11 PSG9 PSMD8 SLC22A4 SLC30A2 TIGIT VTN WNK1
Entrez ID		10225	5817
HPRD ID		06916	01434
Ensembl ID		ENSG00000153283	ENSG00000073008
Uniprot IDs		E9PEJ1 P40200 Q8WUE2	A0A0A0MSA9 A0A0C4DG49 A8K4I1 P15151
PDB IDs		6ARQ	1DGI 1NN8 3EPC 3EPD 3EPF 3J8F 3J9F 3UDW 3URO 4FQP 6ARQ 6ISC 6O3O
Enriched GO Terms of Interacting Partners?
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