DDX39A and DDX39B

Number of citations of the paper that reports this interaction (PubMedID 14667819)
35

Data Source:
HPRD (two hybrid)

		DDX39A	DDX39B
Description		DExD-box helicase 39A	DExD-box helicase 39B
Image		No pdb structure
GO Annotations	Cellular Component	Transcription Export Complex Nucleus Nucleoplasm Cytoplasm Membrane Nuclear Speck	Transcription Export Complex Nucleus Nucleoplasm Spliceosomal Complex U4 SnRNP U6 SnRNP Cytoplasm Nuclear Matrix Nuclear Speck
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATPase Activity Identical Protein Binding	RNA Binding RNA Helicase Activity Protein Binding ATP Binding RNA-dependent ATPase Activity ATPase Activity U6 SnRNA Binding U4 SnRNA Binding Identical Protein Binding ATP-dependent Protein Binding Protein-containing Complex Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome Liver Development RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing RNA Secondary Structure Unwinding MRNA 3'-end Processing Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Translation Viral MRNA Export From Host Cell Nucleus Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Vascular Smooth Muscle Cell Proliferation Negative Regulation Of DNA Damage Checkpoint Positive Regulation Of DNA Biosynthetic Process
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs			Isopropyl Alcohol
Diseases
GWAS			Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Inflammatory bowel disease ( 28067908) Mean platelet volume ( 27863252) Monocyte percentage of white cells ( 27863252) Mosquito bite size ( 28199695) Myositis ( 26291516) Ulcerative colitis ( 28067908)
Interacting Genes		11 interacting genes: CCL14 DDX39B EXOSC9 HIPK2 HNRNPLL PTK2 SARNP SAT1 TERF1 TERF2IP UBE2I	24 interacting genes: ALYREF BARD1 DDX39A DNM2 EXOSC9 FANCA HIPK2 HNRNPLL IL7R LUZP4 NCBP2 PIAS2 RBM39 RPS15A SARNP SREK1 SRPK2 STRN4 TDG THOC3 THOC6 TUBB3 YWHAG ZHX1
Entrez ID		10212	7919
HPRD ID		10861	00805
Ensembl ID		ENSG00000123136	ENSG00000198563
Uniprot IDs		O00148	A0A024RCM3 Q13838
PDB IDs			1T5I 1T6N 1XTI 1XTJ 1XTK
Enriched GO Terms of Interacting Partners?
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