DDX39B and THOC6

Number of citations of the paper that reports this interaction (PubMedID 17190602)
188

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, biochemical, pull down)

		DDX39B	THOC6
Description		DExD-box helicase 39B	THO complex 6
Image			No pdb structure
GO Annotations	Cellular Component	Transcription Export Complex Nucleus Nucleoplasm Spliceosomal Complex U4 SnRNP U6 SnRNP Cytoplasm Nuclear Matrix Nuclear Speck	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Nuclear Body Nuclear Speck
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding RNA-dependent ATPase Activity ATPase Activity U6 SnRNA Binding U4 SnRNA Binding Identical Protein Binding ATP-dependent Protein Binding Protein-containing Complex Binding	RNA Binding
	Biological Process	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome Liver Development RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing RNA Secondary Structure Unwinding MRNA 3'-end Processing Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Translation Viral MRNA Export From Host Cell Nucleus Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Vascular Smooth Muscle Cell Proliferation Negative Regulation Of DNA Damage Checkpoint Positive Regulation Of DNA Biosynthetic Process	RNA Export From Nucleus MRNA Export From Nucleus Apoptotic Process Central Nervous System Development RNA Splicing MRNA 3'-end Processing Negative Regulation Of Apoptotic Process Viral MRNA Export From Host Cell Nucleus
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs		Isopropyl Alcohol
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Inflammatory bowel disease ( 28067908) Mean platelet volume ( 27863252) Monocyte percentage of white cells ( 27863252) Mosquito bite size ( 28199695) Myositis ( 26291516) Ulcerative colitis ( 28067908)
Interacting Genes		24 interacting genes: ALYREF BARD1 DDX39A DNM2 EXOSC9 FANCA HIPK2 HNRNPLL IL7R LUZP4 NCBP2 PIAS2 RBM39 RPS15A SARNP SREK1 SRPK2 STRN4 TDG THOC3 THOC6 TUBB3 YWHAG ZHX1	2 interacting genes: ALYREF DDX39B
Entrez ID		7919	79228
HPRD ID		00805	14504
Ensembl ID		ENSG00000198563	ENSG00000131652
Uniprot IDs		A0A024RCM3 Q13838	Q86W42
PDB IDs		1T5I 1T6N 1XTI 1XTJ 1XTK
Enriched GO Terms of Interacting Partners?
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