WASF2 and PSTPIP1

Number of citations of the paper that reports this interaction (PubMedID 9804817)
21

Data Source:
HPRD (in vivo, in vitro)

		WASF2	PSTPIP1
Description		WASP family member 2	proline-serine-threonine phosphatase interacting protein 1
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GO Annotations	Cellular Component	Ruffle Early Endosome Cytosol Cell-cell Junction Actin Cytoskeleton Lamellipodium SCAR Complex Protein-containing Complex Synapse Extracellular Exosome	Uropod Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Lamellipodium Cleavage Furrow Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Protein Binding SH3 Domain Binding Cadherin Binding Protein Kinase A Binding	Protein Binding Cytoskeletal Protein Binding Identical Protein Binding
	Biological Process	Angiogenesis Ameboidal-type Cell Migration Endocytosis Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Lamellipodium Assembly Viral Process Rac Protein Signal Transduction Lamellipodium Assembly Actin Cytoskeleton Organization Actin Filament-based Movement Megakaryocyte Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Stress Fiber Assembly Lamellipodium Morphogenesis Postsynaptic Actin Cytoskeleton Organization	Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Innate Immune Response
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection
Drugs
Diseases			Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome
GWAS		Systolic blood pressure ( 30578418)	Neurofibrillary tangles ( 31497858)
Interacting Genes		23 interacting genes: ABI1 ABI2 ABI3 ABL1 ACTB ACTR2 ACTR3 APBB1 ARPC3 BAIAP2 BTK CDC42 CYFIP2 DOCK1 FYN GAS7 GRB2 ITSN2 NCKAP1 PACSIN1 PRPF40A PSTPIP1 TCERG1	42 interacting genes: ABL1 AXIN1 BUB3 CCDC172 CD2 CD2AP CHD4 DNM2 EXOC5 FAM90A1 FASLG FBXL18 HMG20A KHDRBS1 LSM4 MEFV MFGE8 MVP NAV2 PCDHB14 PRPF31 PTPN12 PTPN18 RINT1 RTP5 RXRB SDCBP SH2D4A SHBG SPG7 SYCE1 TFIP11 TRAF3IP3 TTC1 TULP3 UBE2W WAS WASF1 WASF2 WASL ZNF175 ZNF688
Entrez ID		10163	9051
HPRD ID		05796	05891
Ensembl ID		ENSG00000158195	ENSG00000140368
Uniprot IDs		Q9Y6W5	A0A0S2Z5P3 O43586
PDB IDs		2A40	2DIL
Enriched GO Terms of Interacting Partners?
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