UBA2 and SUMO1P1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		UBA2	SUMO1P1
Description		ubiquitin like modifier activating enzyme 2	SUMO1 pseudogene 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm SUMO Activating Enzyme Complex	Nucleus
	Molecular Function	Magnesium Ion Binding Protein Binding ATP Binding Transcription Factor Binding Transferase Activity SUMO Activating Enzyme Activity SUMO Binding Small Protein Activating Enzyme Binding Ubiquitin-like Protein Conjugating Enzyme Binding Protein Heterodimerization Activity	Protein Binding Transcription Factor Binding Identical Protein Binding
	Biological Process	Protein Sumoylation Protein Modification By Small Protein Conjugation Positive Regulation Of Protein Sumoylation	Protein Sumoylation PML Body Organization
Pathways		SUMO is conjugated to E1 (UBA2:SAE1) SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is transferred from E1 to E2 (UBE2I, UBC9)
Drugs
Diseases
GWAS			Copper levels ( 26025379) Polycystic ovary syndrome ( 22885925)
Interacting Genes		14 interacting genes: BRIX1 CHEK1 ETV4 NEDD8 PARK7 RAD23B SAE1 SERBP1 SUMO1 SUMO1P1 SUMO2 SUMO3 UBC UBE2I	33 interacting genes: ACTN3 AXIN1 C18orf25 CKS1B EDARADD ESRRG FAM118B FAM200A FHL2 FKBP6 GMCL1 HNRNPC KRTAP9-2 L3MBTL3 LCE2A LCE2D MAPK1IP1L NAB2 PHC1 PIAS1 PIAS2 SATB1 SETBP1 SOX5 STX1A SUMO1 TRAF2 TRIM23 UBA2 UBE2I ZBTB26 ZBTB6 ZNRD2
Entrez ID		10054	391257
HPRD ID		11658
Ensembl ID		ENSG00000126261
Uniprot IDs		Q9UBT2
PDB IDs		1Y8Q 1Y8R 2PX9 3KYC 3KYD 4W5V 5FQ2 6CWY 6CWZ
Enriched GO Terms of Interacting Partners?
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