SLC1A1

Description		solute carrier family 1 member 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Apical Plasma Membrane Cell Junction Early Endosome Membrane Late Endosome Membrane Neuron Projection Synapse Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	L-glutamate Transmembrane Transporter Activity High-affinity Glutamate Transmembrane Transporter Activity Protein Binding Chloride Transmembrane Transporter Activity Glutamate:sodium Symporter Activity Glutamate Binding Cysteine Transmembrane Transporter Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Ion Transport Chemical Synaptic Transmission Positive Regulation Of Heart Rate Glutamate Secretion L-glutamate Transmembrane Transport Cysteine Transport L-glutamate Import D-aspartate Import Across Plasma Membrane L-glutamate Import Across Plasma Membrane L-aspartate Import Across Plasma Membrane Chloride Transmembrane Transport Cysteine Transmembrane Transport
Pathways		Glutamate Neurotransmitter Release Cycle Transport of inorganic cations/anions and amino acids/oligopeptides Defective SLC1A1 is implicated in schizophrenia 18 (SCZD18) and dicarboxylic aminoaciduria (DCBXA)
Drugs		L-Aspartic Acid Glutamic Acid
Diseases		Dicarboxylic aminoaciduria
GWAS		Coronary artery calcification ( 23870195) Metabolite levels ( 23823483) Pancreatic cancer ( 22158540) Response to antipsychotic treatment in schizophrenia ( 29503163) Response to risperidone in schizophrenia ( 29503163) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		7 interacting genes: APP ARL6IP5 EWSR1 LDLRAD1 LMNA PRKCA RNF5
Entrez ID		6505
HPRD ID		00597
Ensembl ID		ENSG00000106688
Uniprot IDs		P43005
PDB IDs
Enriched GO Terms of Interacting Partners?
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