AVPR2

Description		arginine vasopressin receptor 2
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GO Annotations	Cellular Component	Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Endocytic Vesicle Clathrin-coated Vesicle Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	G Protein-coupled Receptor Activity Vasopressin Receptor Activity Protein Binding Peptide Binding
	Biological Process	Regulation Of Systemic Arterial Blood Pressure By Vasopressin Positive Regulation Of Systemic Arterial Blood Pressure Renal Water Homeostasis G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity I-kappaB Kinase/NF-kappaB Signaling Excretion Hemostasis Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Telencephalon Development Positive Regulation Of Protein Ubiquitination Interferon-gamma Production Cellular Response To Hormone Stimulus Response To Cytokine Negative Regulation Of Urine Volume Negative Regulation Of Renal Sodium Excretion Positive Regulation Of Vasoconstriction Membrane Organization
Pathways		Vasopressin-like receptors G alpha (s) signalling events Vasopressin regulates renal water homeostasis via Aquaporins Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI) ADORA2B mediated anti-inflammatory cytokines production
Drugs		Desmopressin Vasopressin Conivaptan Terlipressin M0002 OPC-51803 Tolvaptan
Diseases		Congenital nephrogenic diabetes insipidus (NDI)
GWAS
Interacting Genes		7 interacting genes: ARRB2 AVP C1QTNF1 GNAS GNB1 GNG2 GRK5
Entrez ID		554
HPRD ID		02368
Ensembl ID		ENSG00000126895
Uniprot IDs		P30518
PDB IDs		4JQI 6NI2
Enriched GO Terms of Interacting Partners?
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