WT1 - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Associated Diseases Hide
CASZ1	castor zinc finger 1
CCDC136	coiled-coil domain containing 136
CCDC33	coiled-coil domain containing 33
CEP70	centrosomal protein 70	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
CIAO1	cytosolic iron-sulfur assembly component 1	Cytosolic iron-sulfur cluster assembly
CYSRT1	cysteine rich tail 1
DIRAS3	DIRAS family GTPase 3
DVL2	dishevelled segment polarity protein 2	TCF dependent signaling in response to WNT WNT mediated activation of DVL Signaling by Hippo PCP/CE pathway PCP/CE pathway Asymmetric localization of PCP proteins Degradation of DVL Disassembly of the destruction complex and recruitment of AXIN to the membrane Disassembly of the destruction complex and recruitment of AXIN to the membrane WNT5A-dependent internalization of FZD4 Negative regulation of TCF-dependent signaling by DVL-interacting proteins RHO GTPases Activate Formins Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis WNT5:FZD7-mediated leishmania damping WNT5:FZD7-mediated leishmania damping
DVL3	dishevelled segment polarity protein 3	TCF dependent signaling in response to WNT WNT mediated activation of DVL PCP/CE pathway PCP/CE pathway Degradation of DVL Disassembly of the destruction complex and recruitment of AXIN to the membrane Disassembly of the destruction complex and recruitment of AXIN to the membrane Negative regulation of TCF-dependent signaling by DVL-interacting proteins RHO GTPases Activate Formins WNT5:FZD7-mediated leishmania damping WNT5:FZD7-mediated leishmania damping
EGR1	early growth response 1	Regulation of PTEN gene transcription Regulation of PTEN gene transcription NGF-stimulated transcription NGF-stimulated transcription Interferon alpha/beta signaling
ETV7	ETS variant transcription factor 7
FAM9B	family with sequence similarity 9 member B
FHL2	four and a half LIM domains 2	PPARA activates gene expression
FMR1NB	FMR1 neighbor
GLIS2	GLIS family zinc finger 2		Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
GOLGA2	golgin A2	Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
HMBOX1	homeobox containing 1
IPO8	importin 8	Transcriptional regulation by small RNAs
KPNA4	karyopherin subunit alpha 4	ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
KPNA5	karyopherin subunit alpha 5	ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways

Search Results for: WT1