Search Results for: NF2

78 interactions involving NF2 - neurofibromin 2 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
MDM4 MDM4 regulator of p53
  • Oxidative Stress Induced Senescence
  • Oncogene Induced Senescence
  • Ub-specific processing proteases
  • Regulation of TP53 Activity through Phosphorylation
  • Regulation of TP53 Degradation
  • Regulation of TP53 Activity through Methylation
  • Stabilization of p53
MED28 mediator complex subunit 28
  • PPARA activates gene expression
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
MYBPC2 myosin binding protein C2
  • Striated Muscle Contraction
PXN paxillin
  • GAB1 signalosome
  • VEGFA-VEGFR2 Pathway
  • Smooth Muscle Contraction
  • Localization of the PINCH-ILK-PARVIN complex to focal adhesions
  • Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
  • PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
PYGO2 pygopus family PHD finger 2
  • Formation of the beta-catenin:TCF transactivating complex
  • Deactivation of the beta-catenin transactivating complex
RALGDS ral guanine nucleotide dissociation stimulator
  • p38MAPK events
  • p38MAPK events
  • RAF/MAP kinase cascade
RASSF1 Ras association domain family member 1
  • Non-small cell lung cancer
  • Bladder cancer
  • Nasopharyngeal cancer
SCHIP1 schwannomin interacting protein 1
SDCBP syndecan binding protein
  • Ephrin signaling
  • Neurofascin interactions
  • RIPK1-mediated regulated necrosis
  • Regulation of necroptotic cell death
  • Neutrophil degranulation
SGSM3 small G protein signaling modulator 3
SLC9A3R1 SLC9A3 regulator 1
  • Nephrolithiasis/osteoporosis, hypophosphatemic
SOX3 SRY-box transcription factor 3
  • Deactivation of the beta-catenin transactivating complex
  • Septo-optic dysplasia
  • Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
  • 46,XX disorders of sex development (Disorders of gonadal development), including: Ovotesticular DSD; Testicular DSD; Ovarian dysgenesis
  • Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
SOX4 SRY-box transcription factor 4
  • Deactivation of the beta-catenin transactivating complex
STK11 serine/threonine kinase 11
  • AMPK inhibits chREBP transcriptional activation activity
  • Energy dependent regulation of mTOR by LKB1-AMPK
  • Regulation of TP53 Activity through Phosphorylation
  • FOXO-mediated transcription of cell death genes
  • Peutz-Jeghers syndrome
  • Pancreatic cancer
TARBP2 TARBP2 subunit of RISC loading complex
  • MicroRNA (miRNA) biogenesis
  • Small interfering RNA (siRNA) biogenesis
TSC1 TSC complex subunit 1
  • Macroautophagy
  • Inhibition of TSC complex formation by PKB
  • Energy dependent regulation of mTOR by LKB1-AMPK
  • TP53 Regulates Metabolic Genes
  • TBC/RABGAPs
  • Lymphangioleiomyomatosis (LAM)
  • Tuberous sclerosis complex (TSC); Bourneville-Pringle disease
TTYH2 tweety family member 2
  • Stimuli-sensing channels
TXLNB taxilin beta

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