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TUBA1A |
tubulin alpha 1a |
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
- Gap junction assembly
- MHC class II antigen presentation
- Separation of Sister Chromatids
- Resolution of Sister Chromatid Cohesion
- Regulation of PLK1 Activity at G2/M Transition
- HSP90 chaperone cycle for steroid hormone receptors (SHR)
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Prefoldin mediated transfer of substrate to CCT/TriC
- Formation of tubulin folding intermediates by CCT/TriC
- Post-chaperonin tubulin folding pathway
- Recycling pathway of L1
- Recycling pathway of L1
- Hedgehog 'off' state
- Cilium Assembly
- Anchoring of the basal body to the plasma membrane
- Intraflagellar transport
- RHO GTPases activate IQGAPs
- RHO GTPases Activate Formins
- COPI-mediated anterograde transport
- COPI-dependent Golgi-to-ER retrograde traffic
- COPI-independent Golgi-to-ER retrograde traffic
- Mitotic Prometaphase
- The role of GTSE1 in G2/M progression after G2 checkpoint
- AURKA Activation by TPX2
- Carboxyterminal post-translational modifications of tubulin
- Carboxyterminal post-translational modifications of tubulin
- HCMV Early Events
- Assembly and cell surface presentation of NMDA receptors
- Activation of AMPK downstream of NMDARs
- Aggrephagy
- Aggrephagy
- EML4 and NUDC in mitotic spindle formation
- Sealing of the nuclear envelope (NE) by ESCRT-III
- Kinesins
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- Albendazole
- Vinblastine
- Mebendazole
- Epothilone D
- Patupilone
- CYT997
- 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
- Artenimol
- Phenethyl Isothiocyanate
- Colchiceine
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- Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
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WRN |
WRN RecQ like helicase |
- Processive synthesis on the C-strand of the telomere
- Removal of the Flap Intermediate from the C-strand
- SUMOylation of DNA damage response and repair proteins
- HDR through Single Strand Annealing (SSA)
- HDR through Homologous Recombination (HRR)
- Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
- Resolution of D-loop Structures through Holliday Junction Intermediates
- Homologous DNA Pairing and Strand Exchange
- Processing of DNA double-strand break ends
- Presynaptic phase of homologous DNA pairing and strand exchange
- Regulation of TP53 Activity through Phosphorylation
- G2/M DNA damage checkpoint
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- Defects in RecQ helicases, including: Bloom's syndrome; Werner's syndrome; Rothmund-Thomson syndrome
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sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) pseudogene |
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ACLY |
ATP citrate lyase |
- ChREBP activates metabolic gene expression
- Neutrophil degranulation
- Fatty acyl-CoA biosynthesis
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ACTG1 |
actin gamma 1 |
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- Gap junction degradation
- Formation of annular gap junctions
- Regulation of actin dynamics for phagocytic cup formation
- Regulation of actin dynamics for phagocytic cup formation
- EPHB-mediated forward signaling
- EPH-ephrin mediated repulsion of cells
- Adherens junctions interactions
- Adherens junctions interactions
- Recycling pathway of L1
- Recycling pathway of L1
- VEGFA-VEGFR2 Pathway
- Interaction between L1 and Ankyrins
- Interaction between L1 and Ankyrins
- Cell-extracellular matrix interactions
- RHO GTPases activate IQGAPs
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate Formins
- RHO GTPases Activate Formins
- MAP2K and MAPK activation
- Signaling by moderate kinase activity BRAF mutants
- Signaling by high-kinase activity BRAF mutants
- Signaling by BRAF and RAF fusions
- Paradoxical activation of RAF signaling by kinase inactive BRAF
- Clathrin-mediated endocytosis
- Signaling downstream of RAS mutants
- Signaling by RAF1 mutants
- FCGR3A-mediated phagocytosis
- FCGR3A-mediated phagocytosis
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AHNAK |
AHNAK nucleoprotein |
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ANAPC15 |
anaphase promoting complex subunit 15 |
- Inactivation of APC/C via direct inhibition of the APC/C complex
- APC/C:Cdc20 mediated degradation of Cyclin B
- Autodegradation of Cdh1 by Cdh1:APC/C
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
- Regulation of APC/C activators between G1/S and early anaphase
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Phosphorylation of the APC/C
- APC-Cdc20 mediated degradation of Nek2A
- Separation of Sister Chromatids
- Senescence-Associated Secretory Phenotype (SASP)
- CDK-mediated phosphorylation and removal of Cdc6
- Transcriptional Regulation by VENTX
- Aberrant regulation of mitotic exit in cancer due to RB1 defects
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ANGPTL4 |
angiopoietin like 4 |
- PPARA activates gene expression
- Transcriptional regulation of white adipocyte differentiation
- Assembly of active LPL and LIPC lipase complexes
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ANKRA2 |
ankyrin repeat family A member 2 |
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ANKRD12 |
ankyrin repeat domain 12 |
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AOPEP |
aminopeptidase O (putative) |
- Metabolism of Angiotensinogen to Angiotensins
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ARFIP2 |
ADP ribosylation factor interacting protein 2 |
- Retrograde transport at the Trans-Golgi-Network
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ARNT |
aryl hydrocarbon receptor nuclear translocator |
- Regulation of gene expression by Hypoxia-inducible Factor
- PPARA activates gene expression
- Phase I - Functionalization of compounds
- Endogenous sterols
- Xenobiotics
- Aryl hydrocarbon receptor signalling
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ASPRV1 |
aspartic peptidase retroviral like 1 |
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AZIN1 |
antizyme inhibitor 1 |
- Regulation of ornithine decarboxylase (ODC)
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BCL2L1 |
BCL2 like 1 |
- BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
- Interleukin-4 and Interleukin-13 signaling
- The NLRP1 inflammasome
- RAS processing
- STAT5 activation downstream of FLT3 ITD mutants
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- 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID
- Isosorbide
- Gossypol
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BECN1 |
beclin 1 |
- Macroautophagy
- Ub-specific processing proteases
- Translation of Replicase and Assembly of the Replication Transcription Complex
- Translation of Replicase and Assembly of the Replication Transcription Complex
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- Estradiol
- Estradiol acetate
- Estradiol benzoate
- Estradiol cypionate
- Estradiol dienanthate
- Estradiol valerate
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CARF |
calcium responsive transcription factor |
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CASC3 |
CASC3 exon junction complex subunit |
- Transport of Mature mRNA derived from an Intron-Containing Transcript
- mRNA Splicing - Major Pathway
- mRNA 3'-end processing
- RNA Polymerase II Transcription Termination
- Regulation of expression of SLITs and ROBOs
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
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CCDC180 |
coiled-coil domain containing 180 |
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