FGFBP1 and FIBP

Data Source:
HPRD (in vitro)

		FGFBP1	FIBP
Description		fibroblast growth factor binding protein 1	FGF1 intracellular binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Cell Surface	Nucleus Mitochondrion Endomembrane System Membrane Nuclear Speck
	Molecular Function	Protein Binding Heparin Binding Fibroblast Growth Factor Binding Growth Factor Binding	Fibroblast Growth Factor Binding
	Biological Process	Signal Transduction Cell-cell Signaling Negative Regulation Of Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis	Fibroblast Growth Factor Receptor Signaling Pathway Platelet Aggregation
Pathways		FGFR2b ligand binding and activation
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Asthma ( 31959851) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Psoriasis ( 28537254)
Interacting Genes		6 interacting genes: ASPH FGF1 FGF2 FIBP HSPG2 UBQLN4	9 interacting genes: APP CSNK2A1 CSNK2B DAPK1 FGF1 FGFBP1 GSK3B RNF32 TENM1
Entrez ID		9982	9158
HPRD ID		06371	08492
Ensembl ID		ENSG00000137440	ENSG00000172500
Uniprot IDs		Q14512	O43427
PDB IDs
Enriched GO Terms of Interacting Partners?
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