MED13 and MED23

Data Source:
HPRD (two hybrid)

		MED13	MED23
Description		mediator complex subunit 13	mediator complex subunit 23
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Mediator Complex	Nucleoplasm Transcription Regulator Complex Mediator Complex
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Nuclear Receptor Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Coffee consumption ( 31046077) Initial pursuit acceleration ( 29064472) Objective response to lithium treatment ( 26503763) PR segment ( 24850809)	L-arginine levels ( 25245031) Type 2 diabetes ( 30054458)
Interacting Genes		9 interacting genes: ENO1 ESR1 MED12 MED13L MED23 MED29 MED9 SREBF1 TSC22D2	15 interacting genes: CEBPB CTDP1 ELF3 ESR1 ESR2 ETS1 FOXJ3 MED13 MED9 NCOA6 PUM2 RELA SREBF1 VDR WDTC1
Entrez ID		9969	9439
HPRD ID		07229	05436
Ensembl ID		ENSG00000108510	ENSG00000112282
Uniprot IDs		A0A024QZ75 Q9UHV7	Q05DL5 Q9ULK4
PDB IDs			6H02
Enriched GO Terms of Interacting Partners?
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