MVP and NNT

Data Source:
BioGRID (two hybrid)

		MVP	NNT
Description		major vault protein	nicotinamide nucleotide transhydrogenase
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nuclear Pore Cytoplasm Cytosol Cytoskeleton Membrane Secretory Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Lumen	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respirasome Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Protein Kinase Binding Protein Phosphatase Binding Identical Protein Binding	NAD(P)+ Transhydrogenase (B-specific) Activity NAD(P)+ Transhydrogenase Activity NADP Binding NAD Binding
	Biological Process	Protein Transport Negative Regulation Of Protein Autophosphorylation ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neutrophil Degranulation MRNA Transport Negative Regulation Of Protein Tyrosine Kinase Activity	Negative Regulation Of Protein Phosphorylation Tricarboxylic Acid Cycle NADPH Regeneration Positive Regulation Of Mitochondrial Membrane Potential Oxygen Homeostasis Response To Vitamin Negative Regulation Of Apoptotic Process Cell Redox Homeostasis Reactive Oxygen Species Metabolic Process Cellular Oxidant Detoxification Proton Transmembrane Transport Positive Regulation Of Hydrogen Peroxide Catabolic Process
Pathways		Neutrophil degranulation	Citric acid cycle (TCA cycle)
Drugs			NADH 7-thionicotinamide-adenine-dinucleotide phosphate Nicotinamide adenine dinucleotide phosphate Xanthinol
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Pulse pressure ( 30224653) Subcutaneous adipose tissue ( 29178545)
Interacting Genes		64 interacting genes: ADAMTSL4 BANP C1orf94 CALCOCO2 CAMK2B CKAP4 DISC1 DLX2 DTX2 EPHX2 ESR1 FNDC3B GIT2 GOLGA2 HP IHO1 KCTD9 KPNA2 KPNA3 MDFI MEOX1 MEOX2 MID2 MRTFA MT-CYB NNT NOTCH2NLA NRF1 NTAQ1 PARP4 PIH1D2 PLSCR1 POT1 PSTPIP1 PTEN PTPN11 RAB3IP RBPMS REL RHOXF2 RIMBP3 RNF111 SAXO1 SERTAD1 SKIL SLC2A4 STN1 TCF4 TENT5C TFCP2 TLE5 TOLLIP TP53 TRAF2 TRIM27 TRIM42 TRIP13 TRIP6 TSPOAP1 UBC UBTD2 VAC14 ZBTB32 ZMIZ2	1 interacting genes: MVP
Entrez ID		9961	23530
HPRD ID		05475	09715
Ensembl ID		ENSG00000013364	ENSG00000112992
Uniprot IDs		Q14764 X5D2M8 X5D7K9 X5DNU0	A0A024R0C3 E9PCX7 Q13423
PDB IDs		1Y7X	1DJL 1PT9 1U31
Enriched GO Terms of Interacting Partners?
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