CDC25B and CDC14A

Data Source:
BioGRID (enzymatic study)

		CDC25B	CDC14A
Description		cell division cycle 25B	cell division cycle 14A
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol	Spindle Pole Nucleoplasm Nucleolus Cytoplasm Centrosome Cytosol Nuclear Body Stereocilium Tip Kinocilium Mitotic Spindle Kinociliary Basal Body
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding	Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Oocyte Maturation Protein Phosphorylation Female Meiosis I Positive Regulation Of Cell Population Proliferation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cytokinesis Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Mitotic Cell Cycle Cell Division Positive Regulation Of G2/MI Transition Of Meiotic Cell Cycle	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Regulation Of Exit From Mitosis Sensory Perception Of Sound Positive Regulation Of Cytokinesis Peptidyl-tyrosine Dephosphorylation Cell Division Cilium Assembly Mitotic Cell Cycle Arrest
Pathways		Cyclin A/B1/B2 associated events during G2/M transition Cyclin A:Cdk2-associated events at S phase entry Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase MAPK6/MAPK4 signaling
Drugs		L-cysteic acid
Diseases
GWAS		Basophil percentage of granulocytes ( 27863252) Cognitive decline rate in late mild cognitive impairment ( 26252872) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Estimated glomerular filtration rate ( 31152163 31015462) Systolic blood pressure x educational attainment (some college) interaction (2df) ( 32372009)
Interacting Genes		28 interacting genes: AATK AR AURKA BRSK1 BRSK2 CDC14A CDK1 CDK2 CDK5 CHEK1 CREBBP CSNK2A1 CSNK2B ESR1 FHL3 KAT2B MAPK14 MAPK9 MAPKAPK2 MELK PGR PSME3 SFN YWHAB YWHAE YWHAH YWHAQ YWHAZ	15 interacting genes: AATK ATPAF2 BRAP C14orf119 CDC25B CDC6 CHRM1 FZR1 KIF20A LMTK2 PLK1 POLR2A PTK7 ROR2 TP53
Entrez ID		994	8556
HPRD ID		00307	04614
Ensembl ID		ENSG00000101224	ENSG00000079335
Uniprot IDs		B3KS38 B4DIG0 B4DQZ3 B4DRC3 E1YMX4 G8JLH2 P30305 Q6MZW8	A0A0U1RQX7 A0A2R8YDJ8 B4DY86 Q59EF4 Q9UNH5
PDB IDs		1CWR 1CWS 1CWT 1QB0 1YM9 1YMD 1YMK 1YML 1YS0 2A2K 2IFD 2IFV 2UZQ 3FQT 3FQU 4WH7 4WH9
Enriched GO Terms of Interacting Partners?
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